Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
J Environ Biol ; 2008 Jul; 29(4): 465-9
Artículo en Inglés | IMSEAR | ID: sea-113478

RESUMEN

Thirty-seven species of common seaweeds from the coast of Korea were screened for anti-inflammatory activity Methanol extracts of the seaweeds were tested against mouse ear edema and erythema induced by phorbol myristate acetate. At 40 mg ml(-1) of extract, edema was strongly suppressed by the seaweeds Undaria pinnatifida and Ulva linza, with relative inhibition of 85 and 84%, respectively These two seaweeds also showed the greatest suppression of erythema, with inhibition of 78 and 70%, respectively IC50 values of U. pinnatifida were 10, 15, and 18 mg ml(-1) when inflammation symptoms of edema, erythema, and blood flow, respectively were measured. The IC50 of U. linza was 20, 26, and 31 mg ml(-1) when edema, erythema, and blood flow, respectively, were measured. A linear correlation among inhibition rates of edema, erythema, and blood flow was observed with high confidence.


Asunto(s)
Animales , Antiinflamatorios/farmacología , Velocidad del Flujo Sanguíneo , Relación Dosis-Respuesta a Droga , Oído/patología , Edema/inducido químicamente , Eritema/inducido químicamente , Inflamación/inducido químicamente , Concentración 50 Inhibidora , Corea (Geográfico) , Metanol/química , Ratones , Ratones Endogámicos BALB C , Extractos Vegetales/farmacología , Algas Marinas/química , Acetato de Tetradecanoilforbol
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA