RESUMEN
AbstractCutaneous metastasis is a rare manifestation of visceral malignancies that indicates primarily advanced disease. Due to its low incidence and similarity to other cutaneous lesions, it is not uncommon to have a delayed diagnosis and a shortened prognosis. We describe the case of a patient who presented with a cutaneous nodule in the sternal region as a first sign of malignancy.
Asunto(s)
Anciano de 80 o más Años , Femenino , Humanos , Adenocarcinoma/secundario , Neoplasias Gastrointestinales , Neoplasias Primarias Desconocidas/patología , Neoplasias Cutáneas/secundario , Biopsia , Resultado FatalRESUMEN
Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.
.Asunto(s)
Humanos , Masculino , Adulto Joven , Tumor Glómico/patología , Paraganglioma Extraadrenal/patología , Neoplasias Cutáneas/patología , Tumor Glómico/genética , Mutación , Paraganglioma Extraadrenal/genética , Neoplasias Cutáneas/genética , Piel/patologíaRESUMEN
Tumor of the follicular infundibulum is a rare benign cutaneous adnexal neoplasm with variable clinical presentation. In most cases the diagnosis is made with the help of histopathology, due to lack of a characteristic clinical presentation. The most common form is a solitary lesion, but it can be multiple or eruptive, then called infundibulomatose. This case report illustrates a patient with multiple lesions of tumor of the follicular infundibulum with bizarre aspect and atypical location.
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Neoplasias de Anexos y Apéndices de Piel/patología , Neoplasias Cutáneas/patología , Biopsia , Piel/patologíaRESUMEN
Sarcoidosis is a multisystem granulomatous disease of unknown cause. The osteoarticular involvement in sarcoidosis is rare and is often associated with cutaneous and long-standing chronic multisystem disease. More common in black women, osseous sarcoidosis is difficult to diagnose, with an incidence of 3 to 13%. The most characteristic radiological clinical picture evidences rounded, well-defined cysts, with no periosteal reaction and without peripheral sclerosis. The small bones of hands and feet are the most frequently involved sites. This report aims to demonstrate a rare case of osteoarticular sarcoidosis with characteristic clinical presentation, and highlight the importance of detecting osteoarticular involvement in this pathology.