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2.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (9): 576-577
en Inglés | IMEMR | ID: emr-102969

RESUMEN

The spectrum of plasma cell neoplasm represents indolent conditions like Monoclonal Gammopathy of Undetermined Significance [MGUS] to more aggressive multiple myeloma and plasma cell leukemia. Non-secretory myeloma comprises less than 01% of this spectrum where serum protein electrophoresis and quantitative immunoglobulins remain essentially normal. We are presenting a case report of this rare variant involving the sternum of an adult male


Asunto(s)
Humanos , Masculino , Hipergammaglobulinemia , Electroforesis de las Proteínas Sanguíneas , Cráneo/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Proteínas de Mieloma , Antineoplásicos Alquilantes , Mieloma Múltiple/complicaciones
3.
JCPSP-Journal of the College of Physicians and Surgeons Pakistan. 2008; 18 (3): 176-178
en Inglés | IMEMR | ID: emr-100294

RESUMEN

Imatinib mesylate is a BCR-ABL tyrosine kinase inhibitor used in the management of chronic myeloid leukemia. It is a safe and well-tolerated agent with a few manageable side effects. We are reporting a case of imatinib-related fatal bone marrow aplasia after complete cytogenetic response


Asunto(s)
Humanos , Masculino , Pirimidinas/efectos adversos , Piperazinas/efectos adversos , Proteínas Tirosina Quinasas/antagonistas & inhibidores , Leucemia Mielógena Crónica BCR-ABL Positiva/tratamiento farmacológico
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