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Rev. méd. Chile ; 144(4): 434-441, abr. 2016. ilus, graf, tab
Artículo en Español | LILACS | ID: lil-787114

RESUMEN

Background: Intravenous thrombolysis with recombinant tissue plasminogen activator (rt-PA) reduces disability in patients with ischemic stroke. However, its implementation in Chilean public general hospitals has been slow and faces some difficulties. Aim: To analyze the results of an intravenous thrombolysis protocol implementation in a public general hospital. Material and Methods: During a lapse of 28 months a standardized protocol for intravenous thrombolysis implemented in the emergency room of a public hospital, was prospectively evaluated. Fifty four patients with ischemic stroke were treated and assessed three months later as outpatients. Results: At three months of follow-up, 66.4% of patients subjected to thrombolysis had a favorable evolution, defined as having 0 to 1 points in the modified Rankin scale. Intracerebral hemorrhage rate was 11.1%, including 5.5% of symptomatic intracerebral hemorrhage. Four percent of patients had systemic bleeding complications after thrombolysis. The mortality rate was 14.8%. Conclusions: The success rates, mortality, and complications rate were comparable to the results obtained in international studies, despite of the absence of a stroke unit to manage stroke and its complications.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Anciano , Activadores Plasminogénicos/uso terapéutico , Terapia Trombolítica/métodos , Isquemia Encefálica/tratamiento farmacológico , Accidente Cerebrovascular/tratamiento farmacológico , Fibrinolíticos/uso terapéutico , Factores de Tiempo , Índice de Severidad de la Enfermedad , Infusiones Intravenosas , Encéfalo/diagnóstico por imagen , Tomografía Computarizada por Rayos X , Hemorragia Cerebral/etiología , Hemorragia Cerebral/prevención & control , Isquemia Encefálica/complicaciones , Estudios Prospectivos , Reproducibilidad de los Resultados , Resultado del Tratamiento , Progresión de la Enfermedad , Accidente Cerebrovascular/complicaciones , Hospitales Públicos
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