RESUMEN
Alkaline phosphatase [AP] was studied histochemically in different hamster tissues after Schistosoma mansoni infection. The results showed that the spleen AP increases in early stage after infection, suggesting immunological function for the spleen. In the liver, the AP content increased after the 5th week of infection. The site of the enzyme was shown to be around the endothelium of the blood vessels and blood sinusoids. After infection, the enzyme contents increased in the same sites as before infection, and in addition, there was deposition of the enzyme around and on the ova. In the normal intestine, AP was located in the epithelial surface, which decreased after infection and was replaced by higher content around and on the ova. Kidney AP did not show any change after infection, in quantity or site