Relation between HPV genotype and clinical course of Juvennile - onset recurrent respiratory papillomatosis

The aim of this study was to determine whether viral type HPV-6 and HPV-11 could have influence on the clinical course of recurrent respiratory papillomatosis in children. The detection of viral typing, using the polymerase chain reaction (PCR) was performed on papilloma biopsies of 36 patients at ENT Hospital HCM City from 3/2000 to 3/2004. HPV-6 was detected in 17 patient's biopsies and HPV-11 in 19 biopsies. After the findings, patients infected by HPV-11 have more aggressive than patients infected by HPV-6 (73.7% vs 29.4%; p=0.008). Patients with HPV-11 have higher prevalence of tracheotomy and shorter interval time between two operations than patients with HPV-6

The relationship between juvenile laryngeal papillomas and maternal genital human papillomasvirus (HPV) infection

This study attempted to delineate the relationship between juvenile laryngeal papillomas (JLP) and genital HPV infection in their mothers on 36 pediatric patients JLP with HPV(+) and 14 their mothers with HPV detection from cervical swab at ENT Hospital HoChiMinh city, from March 2000 to March 2004. The results showed that: the rate of genital HPV(+) is 85.7%; the similarity between child and mother genotype is 100% with HPV-11 and 75% with HPV-6. It could have the possibility of HPV transmision from mother to child in recurrent respiratory papillomatosis