Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
Braz. j. med. biol. res ; 33(4): 457-65, Apr. 2000.
Artículo en Inglés | LILACS | ID: lil-258181

RESUMEN

Gap junctions are intercellular channels which connect adjacent cells and allow direct exchange of molecules of low molecular weight between them. Such a communication has been described as fundamental in many systems due to its importance in coordination, proliferation and differentiation. Recently, it has been shown that gap junctional intercellular communication (GJIC) can be modulated by several extracellular soluble factors such as classical hormones, neurotransmitters, interleukins, growth factors and some paracrine substances. Herein, we discuss some aspects of the general modulation of GJIC by extracellular messenger molecules and more particularly the regulation of such communication in the thymus gland. Additionally, we discuss recent data concerning the study of different neuropeptides and hormones in the modulation of GJIC in thymic epithelial cells. We also suggest that the thymus may be viewed as a model to study the modulation of gap junction communication by different extracellular messengers involved in non-classical circuits, since this organ is under bidirectional neuroimmunoendocrine control


Asunto(s)
Humanos , Animales , Ratones , Comunicación Celular/fisiología , Uniones Comunicantes/fisiología , Timo/citología , Conexina 43/fisiología , Citocinas/farmacología , Células Epiteliales , Matriz Extracelular , Uniones Comunicantes/efectos de los fármacos , Hormonas/farmacología , Neurotransmisores/farmacología , ARN Mensajero , Timo/fisiología
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA