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J Environ Biol ; 2007 Apr; 28(2): 283-5
Artículo en Inglés | IMSEAR | ID: sea-113660

RESUMEN

Radical scavenging activity of ethanolic extract of Trianthema triquetra root was investigated against CCl4 in rats. The rats were treated with T. triquetra (100 mg, 200 mg/kg b.w.) for a period of 7 days. Antihepatotoxic effect was studied by assaying the activities of thiobarbituric acid (TBARS), reduced glutathione (GSH), glutathione peroxidase (GPx),catalase (CAT), super oxide dismutase (SOD) and vitamin C (Vit. C). Lipid peroxidation is evidenced by an increase in the value of TBARS and also a distinct diminution in the level of GSH, Vit. C at 200 mg/kg b.w. The activity of antioxidant enzymes, such as GPx, CAT SOD and Vit. E is significantly recovered towards an almost normal level in animals coadministrated with T. triquetra. The maximum protection against CCl4 induced hepatic injury was afforded by the dose of 200 mg/kg b.w. of Trianthema triquetra.


Asunto(s)
Aizoaceae/química , Animales , Ácido Ascórbico/sangre , Tetracloruro de Carbono , Catalasa/sangre , Etanol/química , Depuradores de Radicales Libres/uso terapéutico , Glutatión/sangre , Glutatión Reductasa/sangre , Hepatopatías/inducido químicamente , Masculino , Extractos Vegetales/uso terapéutico , Raíces de Plantas/química , Ratas , Ratas Wistar , Superóxido Dismutasa/sangre , Sustancias Reactivas al Ácido Tiobarbitúrico/metabolismo , Vitamina E/sangre
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