RESUMEN
Odontogenic cysts are jaw lesions that may be misdiagnosed due to lack of complete data. Clinical, radiographic and histopathological correlation is required for the diagnosis of these cysts. The study was thus designed to determine frequency and compare the histopathological features of radicular cysts and odontogenic keratocysts in population of Northern Pakistan. The study was conducted at Sardar Begum Dental College and Khyber College of Dentistry, Peshawar. Non-probability, consecutive sampling technique was used to select 70 cases of odontogenic cysts from 190 cystic jaw lesions. Formalin-fixed paraffin-embedded tissue samples of Odontogenic keratocysts [n=22] and radicular cysts [n=48] were retrieved from the archives of Khyber College of Dentistry and Sardar Begum Dental College, Peshawar. Frequencies of the cysts were calculated. These were then evaluated for histopathological variables which included thickness of epithelial lining, keratinization, foamy macrophages, mucous cells, Rushton bodies, cholesterol crystals and haemosiderin. Chi-square test/ Fishers exact test was applied to compare cysts. The data was analyzed using SPSS version 21. Frequency of the radicular cyst and odontogenic keratocyst was 68.5% [48N] and 31.5% [22N] re-spectively. The histopathological features showed presence of mucous cells, vacuolated cells, spongiosis, micro-abscesses, cholesterol crystals, hemosiderin and inflammatory infiltrate. The radicular cyst was the most prevalent in our study 48[68.5%], followed by the odontogenic keratocysts 22[31.5%]. The histopathological features observed in these cysts are comparable with other populations of Pakistan and abroad
RESUMEN
Present study was carried out to determine the pattern of minor salivary gland tumors, diagnosed at City Medical Laboratory, Peshawar [Pakistan]. The study was conducted at Sardar Begum Dental College using the Anatomical pathology records of City Medical Laboratory, Peshawar from January 2003 to December 2012 and were analyzed by Statistical Program for Social Sciences version 16. A total of 78 cases were diagnosed as minor salivary gland tumors. Out of these 47 were benign and 31 malignant. The male to female ratio for both benign and malignant tumors was 1:1.7. The mean age was 40.39 years. The most common benign tumor was Pleomorphic adenoma [89.3%] and malignant was Adenoid cystic carcinoma [87.09%]. The hard palate was the most common affected site [57.4% in benign and 32.2% in malignant tumors]. The present study showed a different pattern of occurrence of malignant minor salivary gland tumors among the population of Khyber Pahktunkhwa as compared with the European and American population
RESUMEN
To isolate the etiological agent of severe diarrheal outbreak, identification, antibiogram of isolated agent and preventive measures to control the spread of infection. Samples of stool and drinking water supply of affected area collected in Cary- Blair transport medium, inoculated on various media. The isolated strains were identified as responsible for diarrheal outbreak tested against antibiotics. The strain and antibiogram was further confirmed by Agha Khan University Hospital Laboratory in Karachi. Bolan Medical College Hospital, Quetta. Isolation of Vibrio cholerae O1, Ogawa, El Tor, antibiogram against isolated strain, and control of spread of infection. The etiological agent responsible for severe diarrheal disease outbreak was Vibrio cholerae O1, Ogawa El Tor. in which 148 persons affected including all ages and both sexes. Four deaths [2.7%] reported out of these affected patients. The isolated strain was same in all patients and water source. Susceptibility to antimicrobial drugs was determined showing sensitivity to Ampicillin, Choloramphenicol, Ofloxacin, Tetracycline, Nalidixic Acid , Gentamycin and resistance to Polymaxin B, and Cotrimaxazole. The drinking source of water was a shallow well which was sealed and alternative arrangements of drinking water were made from another source. Vibrio cholerae O1, Ogawa El Tor, strains were isolated as etiological agent for severe diarrheal disease outbreak, which was spread through drinking water. The source of drinking water was contaminated due to rain in this area. The isolated strain was most common pathogen in this area for severe diarrheal disease outbreaks, and mostly it spreads through contamination of water source. The strategy applied for prevention of disease was successful and no further case was reported
RESUMEN
Taenia infestation which usually produces mild symptoms like indigestion, diarrhoea, constipation, vomiting, loss of appetite and anaemia may occasionally lead to intestinal perforation and present as haemoperitoneun