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Acta cir. bras ; 32(9): 736-745, Sept. 2017. tab, graf
Artículo en Inglés | LILACS | ID: biblio-886242

RESUMEN

Abstract Purpose: To investigate dynamically the X-ray appearance of cervical degenerative disease induced by unbalanced dynamic and static forces in rats. Methods: A total of 60 Sprague Dawley rats were randomized into test (n=45) and control (n=15) groups, which were randomly subdivided into the one-, three- and six-month post-operative groups. The test group included 10, 15 and 20 rats at the respective corresponding post-operative stage and the control group included five rats at each time-point. By excising cervicodorsal muscles, interspinous ligaments and supraspinous ligament of rats in the test group, the balance of dynamic and static forces on cervical vertebrae was disrupted to establish a rat model of cervical degeneration. Spinal X-ray images were acquired, and intervertebral disc space and intervertebral foramen size were measured at one, three and six months post-operation. The results were analyzed and compared among groups. Results: Cervical dynamic and static imbalance accelerated the appearance of cervical degenerative disease on X-ray. Conclusion: Cervical degenerative disease may be induced by unbalanced dynamic and static forces in rats.


Asunto(s)
Animales , Masculino , Ratas , Degeneración del Disco Intervertebral/diagnóstico por imagen , Fenómenos Biomecánicos , Distribución Aleatoria , Ratas Sprague-Dawley , Modelos Animales de Enfermedad , Degeneración del Disco Intervertebral/etiología
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