RESUMEN
OBJECTIVE: To find out the frequency of carcinoma of gall bladder in the cholecystectomy specimen sent for histopathology
DESIGN: Retrospective study
SETTING: Department of surgery, Liaquat University Hospital, Jamshoro and Depart of Pathology, Liaquat University of Medical and Health sciences Jamshoro
DURATION: From January 2007 to December 2008
METHOD: A retrospective histopathological analysis of specimen collected after cholecystectomies during January 2007 to December 2008 along with patient's notes, hospital records were analyzed. In addition demographic details were also collected. Data was entered into SPSS 13 and analyzed
RESULTS: 521 cases that were operated for cholelithiasis, nineteen were found to have carcinoma of gall bladder with incidence of 3.64%. The age ranged from 35 to 70 years, with mean age of 54 years in females and 55 years in males. Male to female ratio was 1:3.75. Adenocarcinoma [89.47%] was the most common histological variant
CONCLUSION: We conclude that carcinoma Gallbladder is having a high incidence of 3.64%, occurring at an early age with female preponderance. Since preoperative clinical examination and other radiological investigations cannot diagnose it efficiently in asymptomatic cases, therefore we suggest every gallbladder specimen should be routinely subjected to histopathology for early and curable management