Unusual scalp metastasis from follicular thyroid carcinoma

Metastatic tumors presenting as soft tissue lesions are relatively rare, and can be the source of diagnostic confusion both clinically and histopathologically. We present a case of an 82-year-old woman with complaints of painless swelling in the right temporo-occipital junction for 3 months, and with unusual scalp metastasis of thyroid follicular carcinoma. Use of histopathological examinations are significant for determining the tumor type, and arriving at the exact and correct diagnosis

Acinar cell ultrastructure after taurine treatment in rat acute necrotizing pancreatitis

To evaluate the organelle-based changes in acinar cells in experimental acute necrotizing pancreatitis [ANP] after taurine treatment and the association of electron microscopic findings with histopathological changes and oxidative stress markers. The study was performed in February 2005 at Gulhane School of Medicine and Hecettepe University, Turkey. Forty-five rats were divided into 3 groups. Acute necrotizing pancreatitis was induced in groups II and III. Groups I and II were treated with saline and Group III with taurine 1000 mg/kg/day, i.p, for 48 hours. Histopathological and ultrastructural examinations were determined using one-way analysis of variance and Kruskal-Wallis tests. Histopathologic findings improved significantly after taurine treatment. Degree of injury in rough and smooth endoplasmic reticulums, Golgi apparatus, mitochondria and nucleus of acinar cells also decreased with taurine in correlation with biochemical and histological results. Taurine improves acinar cell organelle structure, and ultrastructural recovery in ANP reflects histological improvement