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In humans, one of the major complications of chronic Diabetes Mellitus (DM) is Peripheral Neuropathy. Apparently linked to ischemic Nerve damage, a ravaging puzzle on its pathophysiology, onset prediction, and prognosis is yet to be fully uncovered. Today, what seems to be a major “breakthrough” is the discovery that chronic DM damages signal transduction across Nerve and Muscle tissues, leading to a bad and/or poorly coordinated reflex. The goal of this study was to find in humans, the relationship that binds fasting blood sugar (FBS) with grip muscle strengths and reflex response time. To achieve this, 387 humans were ethically sourced from Ethiope East Local government area of Delta State, Nigeria. Based on their glucometer readings, subjects were then gender-sorted and classified into 3 groups; A (hypoglycaemic), B (normoglycaemic or control), and C (hyperglycaemic). Using the hand-grip dynamometer (HGD) and Meter rule, subjects’ Grip Muscle strengths (GMS) and Reflex Response times (RRT) were respectively obtained and mapped against their corresponding glucometer reading (FBS). Using the Pearson Product moment correlation coefficient, Statistical measure of association (correlation) was conducted on obtained variables, and ANOVA was used to analyse the differences between means of each groups. Though no actual difference(s) was/were found between GMS and RRT, apparently, there was a weak Auditory-FBS relationship in hypoglycaemic females, and a weak GMS-FBS, plus Tactile-FBS correlations in hypoglycaemic males and females respectively.
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Introduction: Recently there has been an increased association between environmental factors and male infertility. Aims: In the present study, the effect of changes in testicular biometric parameters (weight and volume) and testicular function (Sperm count, morphology, testosterone level) in Cadmium chloride administered Wistar rats was studied. Methodology: Twenty male albino Wistar rats were randomized into four groups (n=5). Group A (control) received rat chow and water, while Group B, C and D received 15mg/L, 20mg/L and 25mg/L of Cadmium chloride respectively for 6 weeks. Result: There was a significant (P=.05) and dose dependent decrease in testicular function parameters in the rats and a significant (P=.05) and positive correlation between the biometric parameters and testicular function. Conclusion: The findings showed that Cadmium chloride has a deleterious effect on testicular function and biometric parameters of the testes may be important in the assessment of testicular function.
RESUMEN
Purpose: Reports in Nigeria and other developing countries have indicated a rise in the prevalence of obesity among adults. In identifying at what age in our environment obesity starts becoming a problem; we measured the burden of overweight and obesity among young adults. Methods: Four hundred and sixty four undergraduate students; who were undergoing medical examination as part of admission process; were recruited. Their weight; height and blood pressure (BP) were measured and their body mass index (BMI) was calculated. The prevalence of obesity; overweight and under-nutrition among these students were determined according to international guidelines. Results: The prevalence of obesity (3.4) and undernutrition (3.1) among the students; were similar. Female students had higher prevalence of obesity (4.02) and under-nutrition (3.1) than the males. Overweight was found to be commoner in male subjects (26.78) than in females (20.98). The prevalence of hypertension was 3.4in the study population and was commoner in males (5.9) than in females (0.89). Mean systolic blood pressure and diastolic blood pressure were significantly higher in males than females (p 0.05). Conclusion: Obesity and under-nutrition are prevalent among the fresh undergraduate students. As part of the orientation programme for fresh undergraduate students in Nigerian Universities; nutrition education should be carried out. The need to always conduct blood pressure monitoring for all University students is also recommended