Opsoclonus-Myoclonus in children

Opsoclonus-myoclonus [OPMS] is a rare neurological syndrome of children and adults. Association with neuroblastoma occurs in 20-50% of all cases. We have recently encountered an infant with this syndrome and detailed work up revealed her to have an underlying neuroblastoma. Etiology and pathogenesis of this syndrome have been reviewed, it is important for general paediatricians to recognise this entity in order to initiate investigations and possible treatment