Altered parathyroid hormone, calcium, phosphorus, alkaline phosphatase and albumin in traumatic rhabdomyolysis induced acute renal failure

This study included 15 patients with traumatic rhabdomyolysis complicated by acute renal failure, 8 of them were going fasciotomy followed by haemodialysis and the remainders were going haemodialysis alone. Also 10 control normal subjects were included for comparison. On admission all patients had marked hyperphosphataemia and hypocalcaemia associated with hyperparathyroidism. Our results showed very high significant differences for parathormone with the higher levels in the fasciotomy group

Susceptibility of pathogenic bacteria to augmenting in comparison to other antibiotics

A total of 6241 strains of bacteria were isolated from various clinical specimens and tested in vitro to determine the efficacy of amoxycillin calvulanic acid [Augmentin] in comparison with other commonly used antimicrobial agents. This was done by means of disc diffusion method using Muller-Hinton agar susceptibility plates. 74% of the 1994 strains of Enterobacteriaceae, 97% of 1105 Staphylococcus aureus, 62% of 300 Staphylococcus epidermiditis and all the isolates of streptococci, micrococci and enterococci were inhibited by Augmentin. All the 1289 strains of Pseudomonas species, 89% of Serratia marcescens and 79% of Enterobacter species were resistant to Augmentin. However, Augmentin showed considerably increased activity against Escherichia coli, Klebsiella, Proteus and Acinetobacter species as well as staphylococci when compared with ampicillin. Therefore, Augmentin appears to be a very active drug in empirical treatment of infections caused by Gram-positive cocci mainly as well as many of the Gram-negative Enterobacteriaceae