RESUMEN
A newborn, who had the congenital anomalies including protuberance on the right lower leg, bilateral equinovarus deformity of the feet, genu valgum with knee flexion deformity, syndactyly between the first and the second digit on the right, in addition with the absence of the fifth digit is reported here. Echocardiography revealed a secundum type atrial septal defect. The combination of these congenital defects associated with developmental anomalies of lower extremities. The clinical, radiological findings and pathogenesis of this lower extremity malformation is discussed.
Asunto(s)
Anomalías Múltiples , Ecocardiografía , Fémur/anomalías , Peroné/anomalías , Cardiopatías Congénitas/complicaciones , Cardiopatías Congénitas/diagnóstico , Humanos , Recién Nacido , Imagen por Resonancia Magnética , MasculinoRESUMEN
Hyperpigmentation is one of the cutaneous side effects of chemotherapautic agents, but it is usually accepted as a cosmetic problem. We report a child with yolk sac tumor who developed localized pigmentation after the first course of chemotherapy regimen that included cisplatin, etoposide and bleomycin. The hyperpigmentation was diffuse scattered, flagellate like and linear streaking which was thought to be mainly related to the skin toxicity of bleomycin.
Asunto(s)
Antibióticos Antineoplásicos/efectos adversos , Bleomicina/efectos adversos , Preescolar , Tumor del Seno Endodérmico/tratamiento farmacológico , Femenino , Humanos , Hiperpigmentación/inducido químicamente , Factores de TiempoRESUMEN
We present a male infant with hydrocephalus, cleft lip/palate, micrognathia, club foot, laryngeal stenosis and ostium secundum type atrial septal defect. The karyotype was 46 XY. The combination of malformations observed overlaps with the characteristic findings of hydrolethalus syndrome, Meckel syndrome, Smith-Lemli-Opitz syndrome and pseudotrisomy 13. We discussed the differential diagnosis of the case.
Asunto(s)
Anomalías Múltiples , Labio Leporino , Fisura del Paladar , Anomalías Craneofaciales , Resultado Fatal , Humanos , Hidrocefalia , Recién Nacido , Masculino , Malformaciones del Sistema Nervioso , SíndromeRESUMEN
We report a case of toxic epidermal necrolysis who was successfully treated with intravenous immunoglobin and granulocyte colony-stimulating factor. He had poor prognostic factors such as extensive epidermal loss, neutropenia, acute respiratory distress syndrome and candida sepsis, but nonetheless made a complete recovery.