RESUMEN
To evaluate the diagnostic efficacy of a simple non - invasive transvaginal Sonography [TVS] and transvaginal Doppler sonography in the diagnosis of abnormal endometrial pathology compared to the invasive endometrial biopsy. This study was done on 30 patients with abnormal uterine bleeding from Shibin El-Kom teaching hospital, Al-Hussein university hospital and Menofyia university hospital. All of them were in perimenopausal period. The patients underwent TVS for measurement of endometrial thickness and transvaginal Doppler sonography to measure resistance index [RI] and pulsatility index [PI]. Endometrial biopsy had done for all patients and the results were compared. Endometrial thickness exceeding 6 mm was plotted as a cut-off level for suspecting endometrial pathology. At 9.5 mm. thickness the sensitivity and specificity for diagnosis of endometrial carcinoma were 100% and 87% respectively. On the other hand the RI of 0.79 carries 100% sensitivity and 91% specificity for diagnosis of endometrial carcinoma, and the PI of 2.1 gives 92% sensitivity and 96% specificity for diagnosis of endometrial carcinoma. Combination of trans-vaginal sonography and Doppler transvaginal sonography posses a high sensitivity and specificity that makes them a clinically useful and applicable single test in prediction of endometrial malignancy in cases of abnormal uterine bleeding