Vosodilator effect of pelargonium odoratissimum on isolated rat aorta

The vasodilator effect of Pelargonium odoratissimum was investigated using isolated rat aortic rings. Eethanolic extract has shown a profound relaxing effect on noradrenaline-precontracted aortic rings. There was a difference in the effect in the absence or presence of endothelium. Relaxing effect of the ethanolic extract was obviously more potent in the presence of endothelium. These data clearly indicate that relaxing effect of Pelargonium odoratissimum is partially endothelium-dependent