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1.
Indian J Ophthalmol ; 2013 Nov ; 61 (11): 692
Artículo en Inglés | IMSEAR | ID: sea-155470
2.
Indian Heart J ; 2005 Nov-Dec; 57(6): 655-7
Artículo en Inglés | IMSEAR | ID: sea-3521

RESUMEN

BACKGROUND: The aim of the present study was to investigate whether the von Willebrand factor levels, as a possible indicator of endothelial dysfunction, is increased in hypertrophic cardiomyopathy, and also whether it is related to the clinical status of hypertrophic cardiomyopathy. METHODS AND RESULTS: The study group comprised 29 patients with hypertrophic cardiomyopathy and 29 healthy age- and gender-matched control subjects. There was no significant difference in von Willebrand factor levels between study group (77.0 +/- 23.1%) and control group (88.5 +/- 34.2%). There was no statistically significant difference between control group (88.5 +/- 34.2%) and functional class I/II group (82.0 +/- 24.3%), between control group and functional class III group (67.6 +/- 18.3%) and between functional class I/II group and functional class III group with respect to the von Willebrand factor levels. CONCLUSIONS: The results suggest that von Willebrand factor levels, as a possible indicator of endothelial dysfunction, are not increased in patients with hypertrophic cardiomyopathy and von Willebrand factor levels are not related to functional class in these patients.


Asunto(s)
Adulto , Anciano , Análisis de Varianza , Biomarcadores/análisis , Cardiomiopatía Dilatada/sangre , Estudios de Casos y Controles , Endotelio Vascular/patología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Probabilidad , Pronóstico , Estudios Prospectivos , Valores de Referencia , Medición de Riesgo , Sensibilidad y Especificidad , Índice de Severidad de la Enfermedad , Factor de von Willebrand/análisis
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