School refusal, depression and suicidality in an adolescent girl- the interplay of stress and vulnerability: a case report

The stress vulnerability model emphasizes the interplay of genetic vulnerability, personal characteristics and psychosocial factors in the causation of mental illness. The index case highlights the genesis of psychiatric illness in an adolescent female with a family history of bipolar disorder and substance dependence leading to impaired family interaction and family dynamics. Individual psychotherapy, family therapy and pharmacological management proved beneficial in the index case.

Dependence syndrome and intoxication delirium associated with zolpidem.

The use of zolpidem by general practitioners and specialists alike has increased. Earlier, it was considered safe by physicians, i.e. devoid of dependence potential and the risk of serious adverse events. We report 5 patients seen over a 36-month period at the Post Graduate Institute of Medical Education and Research, which highlight the need for caution in the use of this drug.