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1.
Indian J Dermatol Venereol Leprol ; 2008 Nov-Dec; 74(6): 700
Artículo en Inglés | IMSEAR | ID: sea-52189
2.
Artículo en Inglés | IMSEAR | ID: sea-110545

RESUMEN

BACKGROUND: The epidemiological aspects and diagnostic problems encountered in a rural set up are largely unknown. The present study on cutaneous tuberculosis encompassing clinical, pathological and epidemiological aspects was undertaken at Rajah Muthiah Medical college and Hospital (RMMC&H), a teaching hospital mainly catering to the health needs of a predominantly rural population from villages and hamlets around Chidambaram, a taluq headquarters, located in Cuddalore district ofTamil Nadu. MATERIAL AND METHODS: During the period of study, 5744 cases (82%) of pulmonary tuberculosis and 1261 (18%) of extra-pulmonary tuberculosis were encountered. Cutaneous tuberculosis accounted for 117 (1.67%) of tuberculosis cases. RESULTS: Of the seventy-one patients with cutaneous tuberculosis, 39 had lupus vulgaris and 32 with TBVC. Lupus vulgaris was more prevalent with male pre-ponderance. The maximum incidence was seen in the second decade of life. Both LV and TBVC showed a male pre-ponderance, M:F ratio being 3:2 and 2:1 in LV and TBVC respectively. A majority of patients with LV (27 cases; 69.2%) and TBVC (31 cases; 96.8%) manifested with a single site of involvement. Lower extremities were more commonly involved among patients hailing from poor economic strata who were not habituated to the use of footwear while working out doors. Over crowding was also a contributing factor. The relationships between BCG vaccination and Mantoux test with cutaneous tuberculosis, association with pulmonary tuberculosis in addition to the underlying predisposing socio-economic factors are discussed.


Asunto(s)
Adolescente , Adulto , Anciano , Niño , Preescolar , Femenino , Humanos , India , Masculino , Persona de Mediana Edad , Salud Rural/estadística & datos numéricos , Factores Sexuales , Tuberculosis Cutánea/diagnóstico , Adulto Joven
3.
Indian J Dermatol Venereol Leprol ; 2008 Sep-Oct; 74(5): 513-5
Artículo en Inglés | IMSEAR | ID: sea-52766
4.
Artículo en Inglés | IMSEAR | ID: sea-110497

RESUMEN

Tuberculosis is a major public health problem in both developing and developed countries. Cutaneous Tuberculosis constitutes a minor proportion of extra-pulmonary manifestations of Tuberculosis. Lupus Vulgaris (LV) is one of the clinical variants of Cutaneous Tuberculosis. A case of a large plaque type psoriasiform lesion of lupus vulgaris on the thigh, of 15 years' duration, in an 18-year-old girl is reported. This case highlights the ignorance level among the patients and consequent failure to avail proper anti-tuberculous treatment despite campaign in print and audio visual media.


Asunto(s)
Adolescente , Antituberculosos/uso terapéutico , Biopsia , Nalgas , Niño , Progresión de la Enfermedad , Etambutol/uso terapéutico , Femenino , Humanos , Isoniazida/uso terapéutico , Lupus Vulgar/diagnóstico , Pirazinamida/uso terapéutico , Piridoxina/uso terapéutico , Rifampin/uso terapéutico , Prueba de Tuberculina , Complejo Vitamínico B/uso terapéutico
5.
Artículo en Inglés | IMSEAR | ID: sea-110519

RESUMEN

Tuberculosis Verrucosa Cutis (TBVC) or warty tuberculosis is a variant of cutaneous tuberculosis in patients with good cell mediated immunity (CMI) to Mycobacterium Tuberculosis, while Miliary Tuberculosis is associated with very poor CMI. Two widely different clinical presentations in the same patient are very rare and being reported.


Asunto(s)
Adulto , Pie/microbiología , Dermatosis del Pie/microbiología , Humanos , Masculino , Mycobacterium tuberculosis/aislamiento & purificación , Pene/microbiología , Piel/microbiología , Resultado del Tratamiento , Tuberculosis Cutánea/microbiología , Tuberculosis Miliar/microbiología
6.
Artículo en Inglés | IMSEAR | ID: sea-110504

RESUMEN

Tuberculosis affects the population world wide, more among those living in developing countries. The incidence of tuberculosis registered an upward trend even in developed countries, with the advent of HIV infection. Cutaneous tuberculosis accounts for about 1% of cases of extra-pulmonary tuberculosis. Cutaneous tuberculosis presents with various lesions ranging from ulcerative to proliferative or hyperkeratotic lesions. The lesions may sometimes be associated with marked destruction of the tissues resulting in marked disfigurement, especially when it involves face as seen in cases of Lupus Vulgaris. A case of Lupus Vulgaris in a young woman with extensive ulceration of face which responded to ATT resulting in scarring of the face is reported for its rarity amongst Indian population as against western population.


Asunto(s)
Adulto , Biopsia , Diagnóstico Diferencial , Femenino , Humanos , India , Lupus Vulgar/microbiología , Mycobacterium tuberculosis/aislamiento & purificación , Piel/microbiología
7.
Indian J Dermatol Venereol Leprol ; 2006 Jan-Feb; 72(1): 86
Artículo en Inglés | IMSEAR | ID: sea-52959
8.
Indian J Dermatol Venereol Leprol ; 2005 May-Jun; 71(3): 192-4
Artículo en Inglés | IMSEAR | ID: sea-52976

RESUMEN

Disabling pansclerotic morphea is a rare atrophying and sclerosing disorder of the subcutaneous tissue, muscle and bone. It is characterized by atrophy of the skin, subcutaneous fat, muscle and bone involving half of the face. In some patients the atrophic lesions extend to involve the ipsilateral or contralateral upper and lower limbs with radiological evidence of hemiatrophy. The patients may present with arthralgia, convulsions or cramps. We report a case of a woman with deformity of face, and left upper and lower limbs that had started as an indurated plaque on the left half of forehead at the age of 5 years and had gradually enlarged, followed by the development of atrophic changes in left eye. The case is being reported in view of its rare occurrence.


Asunto(s)
Adulto , Contractura/diagnóstico , Articulación del Codo/fisiopatología , Hemiatrofia Facial/diagnóstico , Femenino , Humanos , Pronóstico , Medición de Riesgo , Esclerodermia Localizada/diagnóstico , Índice de Severidad de la Enfermedad
9.
Indian J Med Microbiol ; 2005 Apr; 23(2): 135-6
Artículo en Inglés | IMSEAR | ID: sea-53608

RESUMEN

Cutaneous larva migrans or creeping eruption is an uncommon parasitic skin infection caused by the filariform larvae of dog or cat hook worms. We report a case of larva migrans on the anterior abdominal wall, in a 52 year old lady, who did gardening as a hobby.


Asunto(s)
Abdomen/parasitología , Albendazol/uso terapéutico , Antihelmínticos/uso terapéutico , Crioterapia , Femenino , Humanos , Larva Migrans/diagnóstico , Persona de Mediana Edad
10.
Indian J Dermatol Venereol Leprol ; 2005 Mar-Apr; 71(2): 134-5
Artículo en Inglés | IMSEAR | ID: sea-52903
11.
Artículo en Inglés | IMSEAR | ID: sea-146947

RESUMEN

Cutaneous tuberculosis presents a diagnostic challenge, as it is difficult to demonstrate the causative organism by histopathology and also culture of organisms from skin lesions is a less rewarding and time consuming process. Aim: Present study was undertaken to evaluate the utility of immuno-histochemical staining to demonstrate Mycobacterium tuberculosis antigen in tissue sections. This is based on the finding that the mycobacterial antigen is the last to disappear from the tissues and thus can be used as a marker of mycobacterial infections. Material & Methods: Fifty randomly selected skin biopsy specimens were subjected to routine histopathological examination to corroborate the clinical diagnosis. Immuno-histochemical study was undertaken to demonstrate mycobacterial antigen. Observations: All the tissue sections were negative for AFB, both by Z-N stain and by culture. Mycobacterial antigen was demonstrable in 68% of cases of cutaneous tuberculosis. The highest positivity was recorded in scrofuloderma (89%), followed by Lupus Vulgaris (69%) and Tuberculosis Verrucosa Cutis (47%). Conclusions: Mycobacterial antigen was demonstrable in majority of cases of cutaneous tuberculosis using polyclonal antiserum. However, since cross reactivity was reported in cases of leprosy and also in some fungal infections, this test by itself cannot be considered as diagnostic. The results should be considered along with other findings.

13.
Indian J Dermatol Venereol Leprol ; 2004 Jan-Feb; 70(1): 59-60
Artículo en Inglés | IMSEAR | ID: sea-52205
14.
Indian J Dermatol Venereol Leprol ; 2003 Nov-Dec; 69(6): 428-9
Artículo en Inglés | IMSEAR | ID: sea-52507
15.
Indian J Dermatol Venereol Leprol ; 2003 May-Jun; 69(3): 214-6
Artículo en Inglés | IMSEAR | ID: sea-51896

RESUMEN

BACKGROUND: Differentiation of cutaneous tuberculosis from other infective granulomas of the skin is difficult due to paucity of the organisms in tissue biopsies. Polymerase chain reaction (PCR) is a newer technique to identify the DNA of Mycobacterium tuberculosis in the tissues. AIM: We examined the utility of PCR as a tool for rapid diagnosis of cutaneous tuberculosis especially in cases negative by ZN staining and culture. MATERIAL AND METHODS: Twenty five random skin biopsies from patients with various types of cutaneous tuberculosis were subjected to PCR. RESULTS: An overall positivity of 64% was observed, which is comparable to other series. Seventy five percent of lupus vulgaris cases, 62.2% of tuberculosis verrucosa cutis and 50% of scrofuloderma cases showed PCR positivity. CONCLUSION: Though useful, the cost and the technique involved limit the use of PCR in developing countries like ours.

16.
Indian J Dermatol Venereol Leprol ; 2001 Nov-Dec; 67(6): 332-3
Artículo en Inglés | IMSEAR | ID: sea-51942

RESUMEN

Rhinosporidiosis is a chronic disease, classically involving the nose and nasopharynx, clinically presenting as polypii. However,disseminated rhinosporidiosis, involving various other sites including lips, conjunctiva, uvula, vagina, larynx. trachea. scalp and skin is also known to occur. A case of rhinosporidiosis, with nasal, oropharyngeal and multiple cutaneous lesions, in a patient who is sero--positive for HIV is reported.

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