1.
Southeast Asian J Trop Med Public Health
;
1987 Mar; 18(1): 52-5
Artículo
en Inglés
| IMSEAR
| ID: sea-34404
RESUMEN
Vaccines prepared from attenuated virus can cause symptomatic viral infection of the central nervous system. In the present study, dengue-2 parental and its live attenuated viruses were tested by intrathalamic and intraspinal injections in rhesus monkeys. The dengue-2 viruses were found to be only very weakly neurovirulent when injected directly into the brain or spinal cord of rhesus monkeys.