Outcome of substitutional urethroplasty by using dorsal onlay buccal mucosal graft: our experience of 10 years

Background: The term urethral stricture is anterior urethral disease, or a scarring process involving the spongy erectile tissue of the corpus spongiosum. Methods: Total 127 patients were included in the study. Patient selection criteria for urethroplasty by using buccal mucosal graft was length of stricture more than 2 cm, deep spongiofibrosis, failed optical urethrotomy for 3 times, adequate oral hygiene and proper buccal mucosa. Results: Length of stricture varied from 3.2 to 14 cm. In first postoperative week, 20.47% (n=26) patients developed minor wound infection culture negative seroma formation in stitch line in the skin. Donor site complications like eating and drinking difficulty, dysguesia, pain, sensitivity, speaking disorders were not found in any patient while oral tightness was noted in 43.30% (n=55) of patients. On postoperative follow-up mean peak urinary flow rate (Qmax) was 28.0 ml/sec (range 20.0-30.6 ml/sec). After a mean follow-up of 8.8 months range (1 month to 33 months) overall success rate was 90.55% (n=115). Conclusions: Buccal mucosa is an excellent graft material for substitution free graft urethroplasty in case of long anterior urethral stricture with excellent success rate. Success rate of dorsal onlay substitution free buccal mucosal graft urethroplasty is affected by length of stricture and aetiology of strictures. Lichen sclerosus having moderate success rate of urethroplasty and higher rate of complication and failure rate in 1-stage buccal mucosal urethroplasty and can be considered for two stage urethroplasty in case of very long stricture of anterior urethra of lichen sclerosus origin.

Analytical Method, Chemistry and Properties of Fructose, Sucrose and Ascorbic Acid in Pear Fruit Juice

Pear is a gently sweet fruit, arich source of several nutrientsincludingfiber, sugar, vitamin C molecules, and potassium. This article reports the history, consumption, Types, health benefits, and diseases of various fruit juices. Carbohydrates, Fructose, sucrose, vitamin C, fibers, vitamins, and minerals are prime constituents present in almost all juices. The nutrition composition, manufacturing technique, processing steps, specification, stability data, contamination, and related details of pear juice are discussed in this review. The pharmacological and functional applications of pear juice like Anti-diabetic, Anti-hyperlipidemic, Anti-inflammatory, and Cardio-protective, etc. are covered with their mechanism of action. The marketed preparation and patents are also highlighted. Moreover, the analytical estimation of active constituents by spectroscopy and chromatography [like UV, HPLC, UPLC, and mass spectroscopy] isexplained in this article. The physic-chemical properties, synthesis, chemistry, biological study, pharmacokinetics, and pharmacodynamics of fructose, sucrose, and ascorbic acid, which are chief phytoconstituents in pear juice, are explained in the present article. This review suggests therapeutic pharmacological andanalytical techniques available for estimating sucrose, fructose, and ascorbic acid analytically and bioanalytically. This will contribute in creating a straightforward and verified procedure that complies with green chemistry.

Corm Yield and Economics of Gladiolus Cultivars Affected by Micronutrients Grown under Open Field Conditions in under Subtropics of Jammu

A field experiment was conducted during the 2019-20 at the Experimental Farm, Division of Vegetable Science & Floriculture, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, to evaluate the effect of micronutrients on corm yield and economics of gladiolus (Gladiolus grandiflorus L.) cv. ‘Nova Lux’. The experiment was laid out in Randomized Block Design with three replications and nineteen treatments. The results revealed that the maximum number of corms per plant, corm weight per plant (118.31 g), diameter of corms (5.74 cm),Yield of corms per plot (1866.33 g), net income per hectare ( Rs 7,18,463.9/ha) and cost- benefit ratio (1:2.34) were obtained with the application of ZnSO4 at 0.2 % and FeSO4 at 0.2 %. However, maximum cormels weight per plant (8.67 g), number of cormels per plant (22.85) and yield of cormels per plot (178.73 g) were recorded with the application of ZnSO4 @ 0.4% + FeSO4 @ 0.4%. Thus, foliar application of micronutrients i,e ZnSO4 at 0.2 % and FeSO4 at 0.2 % proved to be most effective in increasing the production and productivity of gladiolus.

Effect of Micronutrients on Growth and Flowering of Gladiolus (Gladiolus grandiflorus L.) under Subtropics of Jammu

An open field experiment was conducted during 2019-20 at the Experimental Farm, Division of Vegetable Science & Floriculture, Sher-e-Kashmir University of Agricultural Sciences and Technology of Jammu, to evaluate the effect of micronutrients on growth, flowering and yield of gladiolus (Gladiolus grandiflorus L.) cv. ‘Nova Lux’. The experiment was laid out in Randomized Block Design with three replications and nineteen treatments. The different micro-nutrient like Fe, Zn and Mn was taken in different concentrations along with control. The results revealed that maximum plant height (97.74 cm), number of leaves per plant (9.04), leaf length (74.36 cm) and leaf area index (4.14) was recorded with the application of ZnSO4 at 0.2 % and FeSO4 at 0.2 %. Further, among the flowering traits, minimum duration for days taken for 1st floret opening, the maximum spike length (81.86 cm), rachis length (56.76 cm), number of florets per spike 917.69) and weight of the spike (74.78 g) was recorded with the application of ZnSO4 at 0.2 % and FeSO4 at 0.2 %. Thus, foliar application of micronutrients i,e. ZnSO4 at 0.2 % and FeSO4 at 0.2 % proved to be most effective in increasing the growth, flowering and corm production in gladiolus.

Steroidal feedback on photoperiodic induction of testicular growth and development in two bird species.

Present study was performed to demonstrate the effect of exogenous administration of testosterone propionate on photoperiodic induction of testicular growth and development in brahminy myna (Sturnus pagodarum) and baya weaver (Ploceus philippinus). Two groups of brahminy myna and baya weaver (n=5 each) were exposed to15L:9D (group-I) and 9L:15D (group-II), and received 30 µg of TP bird-1 for 15 days. Then, the photoperiod was reversed; the one receiving15L was exposed to 9L and vice versa. Observations on body mass and testis volume were taken at the beginning and at 15 days interval. In brahminy myna, a significant change in body mass occurred under 9L:15D, transfer to 15L:9D, but not under 15L:9D group, transfer to 9L:15D. Also, testes were stimulated under 15L:9D transferred to 9L:15D, but not under 9L:15D transferred to 15L:9D. In baya weaver, body mass increased under 15L:9D and 9L:15D for first 15 days and was maintained until the end of the experiment. Testes enlarged gradually in both groups (15L:9D and 9L:15D transfer to vice versa), but it regressed in 15L:9D group, transferred to 9L:15D after 45 days. Taken together it appears that body mass response indicates the photoperiodic effect and gonadal response indicates the hormonal effect. Finally results conclude that the photoperiod and circulating testosterone levels feedback on to hypothalamus regulates reproductive cycle in these birds.

Waste explosives and other hazardous materials--hazard potential and remedial measures: an overview.

A large amount of energetic materials including propellants, high explosives, pyrotechnics are subjected to disposal either due to expiry of their useful life or rejection in the manufacturing process. The environmental regulations do not allow the hazardous materials for open burning / detonation in view of the health hazard involved in these operations. The present paper describes the hazard potential of energetic materials and associated hazardous chemicals. It also deals with global technological status for remedial measures of hazardous chemicals along with their merits and demerits.

The status of oral hygiene in cleft lip, palate patients after surgical correction.

The cleft lip and palate patients usually present a number of problems viz. altered oral anatomy leading to changes in oral physiology diminishing the self-cleansing ability of individual. The handicapped children are unable to maintain their oral hygiene properly. The present study was formulated with the aim that does normalization of oral anatomy have its effect on improvement of oral hygiene? An assessment of oral hygiene index-simplified was performed between preoperative and postoperative values in the same patient at KGMU and KGDU. A total of 50 cases were recorded in two groups of 25 each: (i) 6 years. The observations are statistically analyzed by paired 't' test to get the significance of results. RESULTS: The data analyzed showed the significant decrease in oral hygiene indices observed in both groups. A relative significance in oral hygiene status following surgery was observed. Both groups expressed greater significance when compared pre and postoperatively which is indicative of considerable improvement of oral hygiene after surgical correction. The study concludes that oral hygiene improves more in older cleft lip-palate cases following reconstruction of palatal vault, premaxilla and anterior lip seal by secondary bone grafting method when compared with oral hygiene indices results in primary periosteoplasty cases. The surgical correction of cleft lip palate enhances self-cleaning ability and better compliance to maintain oral hygiene in children as the age advances.

Radicular dens invaginatus - A case report.

Case report showing classical Radicular dens invaginatus; along with in vitro illustrations of the extracted tooth and RVG (Radiovisiography) after radiopaque dye injection.

Pressure controlled inverse ratio ventilation in acute respiratory distress syndrome patients.

Appropriate ventilatory intervention is life saving in acute respiratory distress syndrome (ARDS). Pressure controlled inverse ratio ventilation (PC-IRV) is the likely mode of ventilation benefiting in extreme conditions of ARDS. However, guidelines when to start PC-IRV is not yet well defined. The ventilation-related dilemma, which we faced in two illustrative cases of ARDS are presented. The first patient presenting clinically with ARDS but with high peak airway pressure (PIP) and low dynamic lung compliance, PC-IRV helped in reducing PIP, improved haemodynamics and the oxygenation of blood. In second patient with similar clinical presentation of ARDS, where although PIP was high but the dynamic compliance was better, the PC-IRV caused deterioration in PaO2. Here, patient rather did better with high PEEP (15 cm H2O) and usual I: E ratio (1:2). It is probable that the dynamic lung compliance (< 20ml/cmH2O), PIP (> 50 cm H2O) at conventional I: E ratio (1:2) ventilation (10 ml/kg) with hypotension might form the basis to develop a scoring system for guidance to switch over to PC-IRV ventilation. Further randomised prospective controlled clinical trials will then be required to establish indication to start PC-IRV in ARDS.

Dentigerous cyst--an attempt to ascertain the normal eruption of involved tooth in child patient.

Dentigerous Cyst, in a young patient, located in the right palatal region, extending from 61 to 55, limited to the right side of mid-palatine suture and treated by marsupialization with post operative follow-up of 6 months has been reported. The involved permanent tooth (21) entrapped in the cyst was not extracted and found to erupt in normal direction.