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Clinics ; 65(10): 1009-1011, 2010. tab
Artículo en Inglés | LILACS | ID: lil-565985

RESUMEN

BACKGROUND: Drug hypersensitivity is responsible for substantial mortality and morbidity, and increased health costs. However, epidemiological data on drug hypersensitivity in general or specific populations are scarce. METHODS: We performed a cross-sectional survey of 1015 university students, using a self-reported questionnaire. RESULTS: The prevalence of self-reported drug hypersensitivity was 12,11 percent (123/1015). The most frequently implicated drugs were non-steroidal anti-inflammatory drugs (45,9 percent) and beta-lactam and sulfonamide antibiotics (25,40 percent). The majority of the patients reported dermatological manifestations (99), followed by respiratory (40), digestive (23) and other (19). Forty-five patients had an immediate type reaction, and 76,72 percent (89) had the drug by oral route. CONCLUSION: The results showed that drug hypersensitivity is highly prevalent in university students, and that nonsteroidal anti-inflammatory drug and antibiotics (beta-lactams and sulfonamide) are the most frequently concerned drugs.


Asunto(s)
Adolescente , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , Hipersensibilidad a las Drogas/epidemiología , Estudiantes/estadística & datos numéricos , Antiinflamatorios no Esteroideos/efectos adversos , Brasil/epidemiología , Estudios Transversales , Hipersensibilidad a las Drogas/clasificación , Prevalencia , Sulfonamidas/efectos adversos , beta-Lactamas/efectos adversos
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