Asunto(s)
Humanos , Masculino , Femenino , Niño , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Adulto Joven , Lepra/epidemiología , Factores de Tiempo , Brasil/epidemiología , Estudios Retrospectivos , Análisis de Varianza , Distribución por Sexo , Distribución por Edad , Evaluación de la Discapacidad , Lepra/fisiopatología , Lepra/patología , Persona de Mediana EdadRESUMEN
Abstract: Leprosy can be classified according to its operational form as paucibacillary or multibacillary. Bacilloscopy integrates its diagnostic armamentarium. Patients with the disease may present leprosy reactions. This study describes the association of bacilloscopy results and the type of operational classification of leprosy in patients with leprosy reactions. Medical records were analyzed at a reference center between 2010 and 2015. Reactions occurred in almost half of the patients, making their identification important. The bacilloscopic and operational characterization indicates a greater occurrence of leprosy reactions in patients with positive bacilloscopy and also in multibacillary.
Asunto(s)
Humanos , Lepra/microbiología , Piel/microbiología , Técnicas Bacteriológicas/métodos , Lepra/clasificación , Lepra/diagnóstico , Mycobacterium leprae/aislamiento & purificaciónRESUMEN
Abstract: Leprosy patients can present reactions during the course of the disease. There are no official data on these reactions in Brazil. We aimed to describe the epidemiological characteristics of patients with such reactions, analyzing information from patient records at a referral center in Campinas (SP), from 2010 to 2015.
Asunto(s)
Humanos , Masculino , Femenino , Persona de Mediana Edad , Lepra/epidemiología , Brasil/epidemiología , Estudios Transversales , Lepra Multibacilar/diagnóstico , Lepra/diagnósticoRESUMEN
Abstract: Brazil is a country with a high prevalence of infectious diseases such as leprosy and leishmaniasis. However, coinfection of these diseases is still poorly understood. We report a case of a patient who presented with lepromatous leprosy and cutaneous-mucosal leishmaniasis at the same period. After clinical, laboratory, and histopathological diagnosis, the treatment was introduced and the patient showed important clinical improvement. He was followed in our outpatient clinic. Both pathologies play an important role in the immune system. Depending on the immune response profile of the host, diseases may present themselves in different ways. In this case, the patient showed a divergent immune response for each disease. We hypothesized that this response is specific for each pathogen.
Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Lepra Lepromatosa/complicaciones , Leishmaniasis Mucocutánea/complicaciones , Coinfección/complicaciones , Lepra Lepromatosa/inmunología , Lepra Lepromatosa/patología , Leishmaniasis Mucocutánea/inmunología , Leishmaniasis Mucocutánea/patología , Coinfección/inmunología , Coinfección/patología , Inmunidad Celular/inmunologíaRESUMEN
Bier´s spot são pequenas máculas hipopigmentadas, circundadas por área eritematosa, transitórias e assintomáticas, distribuídas preferencialmente em membros. De etiologia vascular e fisiopatologia ainda não completamente esclarecida, a maioria dos casos é observada em adultos jovens, com poucos casos até então relatados em adolescentes. Este relato traz o caso de uma adolescente de 14 anos que procurou nosso serviço, relatando apresentar, há dois anos, máculas hipocrômicas em membros inferiores; estas se tornavam mais evidentes quando a paciente permanecia em ortostase e cediam à vitropressão por isquemia da área eritematosa circunjacente.