Extramedullary relapse of multiple myeloma presenting as massive upper gastrointestinal bleeding: a rare complication

No abstract available.

Autologous fascia graft as a biological barrier to silicone application in rabbits

To determine the cellular effects of providing a fascial interface around subcutaneously-placed silicone implants, in terms of capsule thickness, myofibroblast/fibroblast cell count and inflammatory cell count. Interventional, comparative study. Istanbul University Cerrahpasa Medical Faculty, Laboratory of Experimental Animals, Istanbul, Turkey, from May to September 2008. A total of 16 adult New Zealand male rabbits with mean weight of 2508 +/- 360 g were used in the study. Animals were divided into two groups as experiment and control groups with equal number of rabbits in each. Fascia injection was applied on silicone implant in the experiment group and compared with the control group in terms of capsule thickness, myofibroblast/fibroblast cell count and inflammatory cell count. At the end of the experiment, tissue samples were examined macroscopically and microscopically for the above. Statistical analysis of data was performed using student's t-test. A statistically significant difference was found between experiment group and control group in terms of mean capsule thickness, mean myofibroblast and fibroblast cell counts and cell density [p < 0.05, each]. Fascia tissue barrier prevent silicone rod reaction and foreign body reaction developing against silicone prosthesis in the studied animal model

A Case of Lichen Sclerosus et Atrophicus Accompanying Bullous Morphea

Bullous morphea is a rare form of morphea characterized with bullae on or around atrophic morphea plaques. Whereas lichen sclerosus et atrophicus (LSA) is a disease the etiology of which is not fully known, and which is characterized with sclerosis. Coexistence of morphea and LSA has been identified in some cases. Some authors believe that these two diseases are different manifestations which are on the same spectrum. The 70-year-old patient stated herein, presented to us for 6 months with annular, atrophic plaques, ivory color in the middle, surrounded by living erythema, on the front and back of the trunk. Occasionally bulla formation on the plaques on the trunk lateral was identified. Fibrotic and atrophic plaques of ligneous hardness were present on the front side of tibia of both legs. In the histopathologic examination, the lesions were found concordant with bullous morphea and LSA. With colchicine 1.5 mg/day, pentoxifylline 1,200 mg/day, topical calcipotriol ointment and clobetasol propionate cream, the erythema in the patient's lesions faded and softening in the fibrotic plaques was observed. Concomitance of bullous morphea and LSA is a rarely seen, interesting coexistence which suggests a common, as yet unknown, underlying pathogenesis.

Gastric duplication cyst in an adult

Gastric duplication cyst which is a rare anomaly can also be observed in adulthood. Abdominal pain is the cost common complaint in adults and most cases are discovered incidentally by radiological examination or gastric endoscopy. Re-operative diagnosis of gastric duplication is difficult and definitive diagnosis requires findings on laparatomy together with histopathological examination of the lesion. Gastric duplication cyst is primarily managed by complete excision. Gastric duplication cyst was suspected on gastric endoscopy and magnetic resonance imaging [MRI] of the abdomen in a 52-year-old woman presented with abdominal pain. She was treated by complete excision of the cyst and the diagnosis was confirmed with the operative findings and histopathological examination of the removed specimen

Ectopic breast carcinoma

A 47-year-old premenopausal woman had a swelling in right axilla which had been diagnosed as "ectopic breast tissue" with an incisional biopsy. A subcutaneous nodule appeared two years ago. The ectopic breast containing the mass was excised with axillary dissection. It was an invasive ductal carcinoma and metastasis was detected in one lymph node. She received local radiotherapy after 6 cycles of chemotherapy and has now been taking hormonotherapy. Ectopic breast tissue has potential for malignant transformation. As its carcinoma has a worse prognosis and a higher incidence of metastasis because of delayed diagnosis, prophylactic excision may be recommended