RESUMEN
Objective:To provide strategical reference for large-scale colorectal cancer screening with full regional coverage by analyzing the results of the first colorectal cancer screening in the target population in Linhai city,Zhejiang Province. Methods:The target population of 50-74 years old in Linhai were invited to take part in the colorectal cancer screening program from 2020 to 2021.The risk of colorectal cancer of the participants were preliminarily evaluated by questionnaire and qualitative fecal occult blood test(FOBT),and participants with positive screening results were suggested to take colonoscopy test for further evaluation.The screening results were collected and analyzed. Results:A total of 71 942 people were screened from 2020 to 2021,and 15 1 70 of them were found positive in preliminary screening.The positive rate in males was significantly higher than that in females(x 2=724.005,P＜0.001),and the positive rate was highest in the population of 60-69 years old during preliminary screening.The compliance rate of colonoscopy was 24.1 9％with no significant difference between males and females(x 2=0.256,P=0.61 3),showing a decreasing trend as the age increases.From 2020 to 2021,the detection rate of lesions by colonoscopy was 52.92％,with 47 case of colorectal cancer(CRC),333 case of advanced colorectal adenoma,561 case of non-advanced colorectal adenoma and 1 001 case of benign lesions.The detection rate of lesions in males was much higher than that in females(x 2=82.451,P＜0.001).The detection rates of lesions,advanced colorectal adenoma,and non-advanced adenoma showed increasing trends with the age.The compliance rate of colonoscopy,the detection rate of lesions,and the detection rate of CRC,advanced colorectal adenoma,and non-advanced adenoma were 32.94％,69.53％,2.87％,1 6.85％and 1 9.71％,respectively,in participants who were both assessed as high-risk according to questionnaire evaluation and FOBT positive,the highest among all participants.The compliance rate of colonoscopy in 2021 was obviously higher than that in 2020(32.11％vs 1 9.09％,P＜0.001),but no significant difference was found in the detection rate of lesions between 2021 and 2020(P＞0.05). Conclusion:From 2020 to 2021,the compliance rate of colonoscopy was low and the detection rate of colorectal lesions was high during the screening of colorectal cancer in the target population in Linhai,Zhejiang Province.It is necessary to enhance the public awareness of the importance of colorectal cancer screening,standardize the enrollment criteria,and improve the compliance of colonoscopy,in orderto give full play to primary screening in the general public.
RESUMEN
Objective To observe the change situation of body metabolism and gastrointestinal function of patients with laparoscopic radical resection of colorectal cancer during the perioperative period.Methods 56 patients with colorectal cancer who were treated with radical resection in our hospital from May 2015 to July 2016 were selected as the research subjects.56 surgical patients were divided into control group (conventional open surgery group,28 cases) and observation group (laparoscopic surgery group,28 cases) by the random number table.The indexes of protein metabolism,lipid metabolism indexes and gastrointestinal function of surgical patients in two groups during the perioperative period were detected and compared.Results The protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in two groups before the surgery had no statistical significance (all P ＞ 0.05),while the protein metabolism indexes,lipid metabolism indexes and gastrointestinal function indexes of surgical patients in two groups after the surgery all had significant differences,and they were all better than those of control group (all P ＜ 0.05).Conclusions The body metabolism and gastrointestinal function indexes fluctuations of patients with laparoscopic radical resection of colorectal cancer during the perioperative period are smaller than those of open surgery,so the laparoscopic radical resection is more suitable to the patients with colorectal cancer.