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Pesqui. bras. odontopediatria clín. integr ; 20: e0012, 2020. tab, graf
Artículo en Inglés | BBO, LILACS | ID: biblio-1135525

RESUMEN

Abstract Objective: To determine the in vitro antibacterial effect of different concentrations of the ethanol extract of Plantago major (plantain) on Porphyromonas gingivalis and Fusobacterium nucleatum. Material and Methods: Bacterial susceptibility tests were used in conjunction with the agar diffusion test and the minimum inhibitory concentration (MIC) test using the broth macrodilution technique. Results: Different concentrations of ethanol extract (25%, 50%, 75% and 100%) dissolved in 70% ethanol were used, with a positive control (0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride) and a negative control (70% alcohol). The extracts at 75% and 100% showed inhibition halos against both strains studied. With 0.12% chlorhexidine + 0.05% cetyl-pyridinium chloride, inhibition halos averaged 14.9 mm, in contrast to 70º alcohol, where no bacterial inhibition was observed. The MIC was 50% for both species. Conclusion: The ethanol extract of Plantago major presents an in vitro antibacterial effect on Porphyromonas gingivalis, they may have potential applications in food and pharmaceutical products.


Asunto(s)
Plantas Medicinales/microbiología , Técnicas In Vitro/métodos , Plantago major , Porphyromonas gingivalis , Bacterias Gramnegativas/inmunología , Perú/epidemiología , Preparaciones Farmacéuticas , Pruebas de Sensibilidad Microbiana , Análisis de Varianza , Fusobacterium nucleatum , Estadísticas no Paramétricas , Agar , Microbiología
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