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Rev. Soc. Bras. Med. Trop ; 51(3): 352-356, Apr.-June 2018. tab
Artículo en Inglés | LILACS | ID: biblio-1041467

RESUMEN

Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Adulto Joven , Candida/efectos de los fármacos , Candidiasis Bucal/diagnóstico , Infecciones Oportunistas Relacionadas con el SIDA/diagnóstico , Antifúngicos/farmacología , Brasil , Candida/aislamiento & purificación , Candida/clasificación , Candidiasis Bucal/microbiología , Farmacorresistencia Microbiana , Pruebas de Sensibilidad Microbiana , Fluconazol/farmacología , Anfotericina B/farmacología , Técnicas de Tipificación Micológica , Infecciones Oportunistas Relacionadas con el SIDA/microbiología , Itraconazol/farmacología , Persona de Mediana Edad
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