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Objective:To explore the e ects of clinical treatment and protection on endothelial function of early essential hypertension patients treated with YiNianJiangYa(YNJY) soup in southern Guangdong area.Methods:79 early essential hypertension cases with traditional Chinese medicine(TCM) syndrome of phlegm stasis blocking collaterals,excess of liver yang were randomly divided into treatment and control groups,treated with YNJY soup and TianMaGouTeng(TMGT) soup respectively for two courses of treatment.Di erences of clinical treatment e ect,blood pressure and pulse pressure after treatment,as well as plasma endothelin-1(ET-1) and von Willebrand factor(vWF) between the two groups were measured.Results:The clinical total e ective rate of treatment group was higher than that of control group(P 0.05).Conclusion:YNJY soup can signi cantly improve clinical treatment e ect of the early essential hypertension patients,has good e ect of decreasing blood pressure and no obvious side e ects.It has many e ects that reduces PP and the levels of plasma ET-1,vWF,may be related to protection of endothelial function,thereby improve the artery exibility.
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Objective To explore the relationship of TCM syndromes in chronic heart failure (CHF) with left ventricular mass index (LVMI) and left ventricular ejection fraction (LVEF). Methods Two hundred and ninety-six CHF patients were classified into the syndromes of Qi deficiency (21 patients), Qi deficiency and blood stasis (98), fluid retention due to Qi deficiency and blood stasis (72), blood stasis due to the deficiency of Qi and yang (56), and blood stasis and fluid retention due to the deficiency of Qi and yang (49). LVMI and LVEF in different syndromes were campared.Results LVMI presented an increasing sequence and LVEF presented a decreasing sequence in the syndromes of Qi deficiency, Qi deficiency and blood stasis, fluid retention due to Qi deficiency and blood stasis, blood stasis due to the deficiency of Qi and yang, and blood stasis and fluid retention due to the deficiency of Qi and yang. Between the syndromes of Qi deficiency, Qi deficiency and blood stasis, and fluid retention due to Qi deficiency and blood stasis, there were significant differences of LVMI and LVEF (P0.05), but LVMI and LVEF in these two syndromes differed from those in the former three syndromes (P