Severe form of lymphocutaneous sporotrichosis: a case report

ABSTRACT Sporotrichosis is the most frequent subcutaneous mycosis in Latin America. It is caused by species of the genus Sporothrix. Infection in humans occurs through the entry of the fungus into the skin. Zoonotic outbreaks involving cats in the transmission of the disease have been frequently reported. The lymphocutaneous form is the most commonly observed and the upper limbs are the most affected sites. We report a case of a 64-year-old healthy female patient with a lymphocutaneous form with rapid progression of lesions, which was refractory to initial treatment with itraconazole. Treatment with liposomal amphotericin B was performed with a satisfactory resolution, but aesthetic and functional sequelae in the left upper limb were installed.

Post-surgical atypical mycobacteriosis in 125 patients in Rio de Janeiro

Abstract INTRODUCTION: The growing incidence of post-surgical atypical mycobacteriosis (PSAM) may be related to the increased use of low- and medium-complexity video-assisted surgery. METHODS: Between April 2007 and June 2009, 125 patients were referred from the State Health Department of Rio de Janeiro for the treatment of confirmed, probable, or suspected PSAM. RESULTS: Laparoscopic cholecystectomy was the most frequent surgical procedure (48.8%) among patients. Clarithromycin, ethambutol, and terizidone were used to treat 113 patients for a mean duration of 226 days. CONCLUSIONS: Despite the need for multidrug therapy and long treatment duration, most included patients adhered to treatment and experienced cure without relapse.

Estudo clínico-epidemiológico de 1.001 casos de doença meningocócica no Instituto Estadual de Infectologia Säo Sebastiäo 1983-1988 / Clinical-epidemiological study of 1.001 cases of meningococcal diseases in the Säo Sebastiäo Institute of Infectolohy in the period 1983-1985

A thousand and one cases were revised in retrospective of the meningococcal disease in the Säo Sebastiäo Institute of Infectology in the period 1983-1988. Tjhe criteria for inclusion were: symptoms compatible with meningococcal diseae (petechiae and/or purpura associated or not to meningitidis), detection of gram negative diplicocci, test of the latex and/or positive culture in the CSF for N. meningitis. Tje progressive increase occurred in the number of cases without having any lost in the older age group. Predominance remained of 78% in children of 12 years, bein 46% in children of 4 years, with a greater incidence in males. The greater number of cases occured in the second half of the year. The death rate remained about 15%, and the death occurred mainly in the first 24 hours. The diagnosis was made on a bacteriological bais in 83.2% of the cases. Of the total of 805 cultures realized 33.7% were positive but not identified, 7.8% of group A, 31.3% of the group B, 5.4% of the group C and 21.6% negtive. A predominance occurred of the serogroup b beginning in 1985. The clinical form more frequent was the meningoencephalitis 42.7%, followed by meningitis with purpura 36%, purpura with meningitidis and shock 10.9%, purpura with shock 6.8%, and purpura without meningitidis 2.7%. Deafness was the most common residual effect totalizing 3% of the cases