RESUMEN
Choroidal osteoma is an unusual form of intraocular calcification seen in otherwise healthy eyes. It is a benign idiopathic osseous tumor of the choroid, typically seen in young females. Choroidal neovascular membrane (CNVM) is a complication seen in one-third of these patients and carries a poor visual outcome. We report a case of a 25-year-old hyperthyroid female with choroidal osteoma and subfoveal CNVM in her left eye which was successfully treated using low-fluence photodynamic therapy (PDT) with verteporfin followed by a single injection of intravitreal ranibizumab.
Asunto(s)
Adulto , ANTIBODIES, MONOCLONAL, HUMANIZED ADMINISTRATION & , Neoplasias Óseas/complicaciones , Neoplasias Óseas/diagnóstico , Neoplasias Óseas/tratamiento farmacológico , Neoplasias de la Coroides/complicaciones , Neoplasias de la Coroides/diagnóstico , Neoplasias de la Coroides/tratamiento farmacológico , Neovascularización Coroidal/diagnóstico , Neovascularización Coroidal/tratamiento farmacológico , Neovascularización Coroidal/etiología , Diagnóstico Diferencial , Femenino , Estudios de Seguimiento , Humanos , Inyecciones Intravítreas , Microscopía Acústica , Osteoma/complicaciones , Osteoma/diagnóstico , Osteoma/tratamiento farmacológico , Fotoquimioterapia/métodos , Tomografía de Coherencia Óptica , Agudeza VisualRESUMEN
Angioid streaks also called Knapp striae are small breaks in the Bruch's membrane and have been reported with a host of systemic diseases. Rupture of streaks or development of secondary choroidal neovascular membrane (CNVM) carries a dismal visual prognosis. We report the successful treatment of CNVM secondary to Paget's disease using low fluence photodynamic therapy (PDT) and intravitreal ranibizumab.