Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 6 de 6
Filtrar
1.
Journal of Korean Medical Science ; : e169-2018.
Artículo en Inglés | WPRIM | ID: wpr-714819

RESUMEN

This nationwide, prospective cohort study evaluated pulmonary function and radiological sequelae according to infection severity in 73 survivors from the 2015 Middle East respiratory syndrome (MERS) outbreak in Korea. Patients with severe pneumonia in MERS-coronavirus infection had more impaired pulmonary function than those with no or mild pneumonia at the 1-year follow-up, which was compatible with the radiological sequelae. Severe pneumonia significantly impairs pulmonary function and makes long radiological sequelae in MERS.


Asunto(s)
Humanos , Estudios de Cohortes , Coronavirus , Infecciones por Coronavirus , Estudios de Seguimiento , Corea (Geográfico) , Medio Oriente , Neumonía , Estudios Prospectivos , Sobrevivientes
2.
Journal of Korean Medical Science ; : 1440-1444, 2017.
Artículo en Inglés | WPRIM | ID: wpr-200239

RESUMEN

Zika is a re-emerging, mosquito-borne viral infection, which has been recently shown to cause microcephaly and Guillain-Barré syndrome. Since 2015 the number of infected patients has increased significantly in South America. The purpose of this study was to identify the epidemiologic and clinical characteristics of patients with Zika virus (ZIKV) infections in Korea. Patients who had visited areas of risk and tested positive in the ZIKV reverse transcriptase polymerase chain reaction (RT-PCR) in blood, urine, or saliva specimens were included. The first Korean case of ZIKV infection was reported in March 2016, and 14 cases had been reported by October 2016. The median age of the patients was 34 years (19–64 years). Ten patients had been exposed in Southeast Asia and 4 in Latin America. Rash was the most common symptom (92.9%; 13/14), followed by myalgia (50.0%; 7/14), and arthralgia (28.6%, 4/14). There were no neurologic abnormalities and none of the patients was pregnant. Results of biochemical tests were normal. Positivity rates of RT-PCR for ZIKV in serum, urine, and saliva were 53.8%, 100.0%, and 83.3%, respectively in the first week of symptoms. In conclusion, 14 patients with ZIKV infections were reported in Korea by October 2016 and all of them had mild clinical symptoms.


Asunto(s)
Humanos , Artralgia , Asia Sudoriental , Epidemiología , Exantema , Síndrome de Guillain-Barré , Corea (Geográfico) , América Latina , Microcefalia , Mialgia , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa , Saliva , América del Sur , Esparcimiento de Virus , Virus Zika
3.
Journal of Korean Medical Science ; : 715-723, 2016.
Artículo en Inglés | WPRIM | ID: wpr-195408

RESUMEN

In Republic of Korea, a 7-valent pneumococcal conjugated vaccine (PCV7) was licensed for use in infants in 2003, and 13-valent PCV (PCV13) replaced it since 2010. We investigated trends in serotype distribution and antibiotic susceptibility of pneumococcal isolates from adult patients with invasive pneumococcal diseases (IPD). Invasive pneumococcal isolates from adult patients of ≥ 16 years of age were collected from 1997 to 2012. Serotypes of the isolates were determined by the Quellung reaction. Distribution of serotypes was analyzed according to the vaccine types. Antibiotic susceptibility was tested by using E-test strips. A total of 272 invasive pneumococcal isolates were included. The most common serotypes were serotype 19F (8.5%, 23/272), and serotype 3 (8.1%, 22/272), and 24.6% (67/272) of the isolates were of non-vaccine serotypes. Of the 272 isolates, 2.6% (7/272) were penicillin MICs of ≥ 4 µg/mL. The proportion of the PCV13 serotypes decreased from 63.3% (50/79) in 1997-2003 to 48.6% (17/35) in 2011-2012, whereas that of non-vaccine serotypes was 26.6% (21/79) and 25.7% (9/35), respectively, for the same periods. The proportion of the PCV13 serotypes showed a decreasing trend among adult patients with IPD over the study period.


Asunto(s)
Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven , Antiinfecciosos/farmacología , Ceftriaxona/farmacología , Pruebas de Sensibilidad Microbiana , Penicilinas/farmacología , Infecciones Neumocócicas/tratamiento farmacológico , República de Corea , Serogrupo , Serotipificación , Streptococcus pneumoniae/efectos de los fármacos
4.
Infection and Chemotherapy ; : 17-21, 2012.
Artículo en Inglés | WPRIM | ID: wpr-141450

RESUMEN

We describe a case of idiopathic CD4+ T-lymphocytopenia (ICL) in a 59-year-old patient who presented with various opportunistic infections. The patient was diagnosed with disseminated Mycobacterium avium infection, cytomegalovirus colitis and retinitis, and esophageal candidiasis. He was successfully treated with anti-mycobacterial drugs, ganciclovir, and fluconazole, respectively. However, the patient was diagnosed with primary central nervous system lymphoma, and then died of a Trichosporon beigelii sepsis during the 2nd cycle of systemic chemotherapy.


Asunto(s)
Humanos , Persona de Mediana Edad , Candidiasis , Sistema Nervioso Central , Colitis , Infecciones por Citomegalovirus , Fluconazol , Ganciclovir , Linfoma , Linfopenia , Mycobacterium avium , Infecciones Oportunistas , Retinitis , Sepsis , Linfocitopenia-T Idiopática CD4-Positiva , Trichosporon
5.
Infection and Chemotherapy ; : 229-233, 2006.
Artículo en Coreano | WPRIM | ID: wpr-721740

RESUMEN

Cryptoccocosis occurs more frequently in immunocompromised hosts such as patients with AIDS, lymphoma, leukemia and other debilitating diseases. Pulmonary cryptococcosis can occur in the absence of any recognized immunodeficiency and cryptococcal meningitis can occur rarely during pregnancy. Although it is extremely rare, we encounter the reports of case of cryptococcal pneumonia and combined cryptococcal meningitis during pregnancy. We present here that 36-year-old pregnant woman, who was previously healthy, with cryptococcal meningoencephalitis and cryptococcal pneumonia was treated with amphotericin B and flucytosine. The maternal outcome was favorable, and there is no evidence of congenital infection in the newborn.


Asunto(s)
Adulto , Femenino , Humanos , Recién Nacido , Embarazo , Anfotericina B , Criptococosis , Flucitosina , Huésped Inmunocomprometido , Leucemia , Linfoma , Meningitis Criptocócica , Meningoencefalitis , Neumonía , Mujeres Embarazadas
6.
Infection and Chemotherapy ; : 229-233, 2006.
Artículo en Coreano | WPRIM | ID: wpr-722245

RESUMEN

Cryptoccocosis occurs more frequently in immunocompromised hosts such as patients with AIDS, lymphoma, leukemia and other debilitating diseases. Pulmonary cryptococcosis can occur in the absence of any recognized immunodeficiency and cryptococcal meningitis can occur rarely during pregnancy. Although it is extremely rare, we encounter the reports of case of cryptococcal pneumonia and combined cryptococcal meningitis during pregnancy. We present here that 36-year-old pregnant woman, who was previously healthy, with cryptococcal meningoencephalitis and cryptococcal pneumonia was treated with amphotericin B and flucytosine. The maternal outcome was favorable, and there is no evidence of congenital infection in the newborn.


Asunto(s)
Adulto , Femenino , Humanos , Recién Nacido , Embarazo , Anfotericina B , Criptococosis , Flucitosina , Huésped Inmunocomprometido , Leucemia , Linfoma , Meningitis Criptocócica , Meningoencefalitis , Neumonía , Mujeres Embarazadas
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA