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Acta Physiologica Sinica ; (6): 548-556, 2018.
Artículo en Chino | WPRIM | ID: wpr-687796

RESUMEN

The vertebrate vascular system development is a very important and complicated process. MicroRNAs regulate gene expression at transcriptional and post-transcriptional levels and play important roles in many physiological and pathological processes. MicroRNAs mainly participate in the regulation of vascular smooth muscle cell and vascular endothelial cell development. In this paper, we summarize the recent progress regarding the microRNAs involved in the vascular development. In particular, we focus on the microRNAs including miR-126, miR-17/92 family in endothelial cell's regulation, and miR-143/145 family, miR-21 in vascular smooth muscle cell's regulation. The future research on the role of microRNAs in vascular development is also prospected.

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