RESUMEN
Objective To compare the detection rate of esophageal and cardiac mucosal lesions be?tween screening endoscopy and conventional routine endoscopy. Methods Using iodine staining,a total of 8 918 patients aged 40?69 were screened for esophageal and cardiac early cancer in Xianju and Tiantai county of Zhejiang Province from January 2010 to July 2013.Matched with age, data of 43 834(the conven?tional group) patients who underwent routine endoscopy during the same time period were also retrieved. The detection rates of esophageal and cardia mucosa lesions in both groups were compared and analyzed. Results The detection rate of esophageal mucosal lesions in screening group was significantly higher than that in the conventional group[7?? 48%(667/ 8 918)VS 2?? 17%(953/ 43 834),P0?? 05). The detection rates of low grade intraepithelial neoplasia, high grade intraepithelial neoplasia and mucosa cancer and total detection rates between 2 groups were similar(P>0?? 05). Conclusion Through training, endoscopists can grasp the skills of finding esophageal mucosal lesions. Iodine staining should be used as addition to conventional endos?copy in areas with high incidence of esophageal cancer. Conventional white light endoscopy plays a limited role in detection of cardia mucosal lesion, depending on joint inspection of other related methods.