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International Journal of Oral Science ; (4): 40-40, 2021.
Artículo en Inglés | WPRIM | ID: wpr-922467

RESUMEN

The first branchial arch (BA1), which is derived from cranial neural crest (CNC) cells, gives rise to various orofacial tissues. Cre mice are widely used for the determination of CNC and exploration of gene functions in orofacial development. However, there is a lack of Cre mice specifically marked BA1's cells. Pax2-Cre allele was previously generated and has been widely used in the field of inner ear development. Here, by compounding Pax2-Cre and R26R-mTmG mice, we found a specific expression pattern of Pax2


Asunto(s)
Animales , Ratones , Proteína Morfogenética Ósea 4 , Región Branquial , Células Madre Mesenquimatosas , Cráneo
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