Quality Standard of Zhikuoning Mixture / 中国药房

OBJECTIVE:To establish the quality standard of Zhikuoning mixture.METHODS:Scutellaria baicalensis,Morus alba,Citrus aurantinm,Salvia miltiorrhiza in the preparation were identified by TLC,and the content of baicalin in Zhikuoning mixture was determined by HPLC.RESULTS:The TLC spots were clear and well-isolated yet without interference from negative control.The linear range of Baicalin was 15.81～252.96 ?g?mL-1(r=0.999 9)and its average recovery was 101.8%(RSD=1.80%,n=9).CONCLUSION:The established quality standard can be used for the quality control of Zhikuoning mixture.