RESUMEN
ABSTRACT Many factors can interfere with glycemic control in patients with type 2 diabetes mellitus and this patient group has an increased risk of experiencing drug-related negative outcomes (DNO). The aim of this study was to identify the predictive factors of unsatisfactory glycemic control and DNO in this group of patients. A cross-sectional study was conducted collecting data from prescriptions and interviews with 100 patients of the Endocrinology Clinic of the Hospital Complex of Sorocaba, São Paulo, Brazil. Variables associated with unsatisfactory glycemic control were determined and the DNO associated with antidiabetic drugs identified. Age (<65 years) (OR=4.09), family history of diabetes (OR=3.24), use of combined therapy to treat diabetes (2-4 antidiabetic drugs) (OR=5.13) and presence of DNO (OR=5.92) were found to be predictive factors for poor patient glycemic control. DNO were observed in 49% of the patients and were caused predominantly by ineffectiveness in patients with poor glycemic control (p<0.05). There was no significant difference between groups (satisfactory and unsatisfactory glycemic control) for DNO caused by safety issues (p>0.05). Characterization of the profile of patients with uncontrolled diabetes and of aspects associated with drug treatment can contribute to the planning of interventions to improve patient care
Asunto(s)
Humanos , Masculino , Femenino , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Hipoglucemiantes/efectos adversos , Pacientes/clasificación , Glucemia/efectos de los fármacos , Índice Glucémico , Complicaciones de la Diabetes/clasificación , Diabetes Mellitus Tipo 2/clasificación , Diabetes Mellitus Tipo 2/complicaciones , Reacciones Falso NegativasRESUMEN
Os linfomas de tireoide são uma forma rara de tumor que acomete, sobretudo, mulheres acima de 40 anos. Apresenta-se com quadro de aumento do volume cervical súbito, associado a sintomas compressivos e o diagnóstico envolve análise citológica e métodos complementares. O tratamento inclui quimioterapia e radioterapia com boa resposta clínica. A seguir, relataremos um caso de linfoma de tireoide e discutiremos o diagnóstico e tratamento.