RESUMEN
Many different methods have been used in an effort to provide adequate analgesia after knee surgery. The goal of this study was comparison analgesic effect of. In a double-blind clinical trial study, 96 ASA physical status I-II patients ranging 20-45 years undergoing knee arthroscopic meniscectomy. Patients were allocated to groups receiving I.V sufentanil, intraarticular sufentanil 10 micro g, or Sufentanil 10 micro g plus Methylprednisolone 40 mg at the end of arthroscopy during general anesthesia. Postoperatively, pain levels at rest and during movement [i.e., active flexion of the knee] were measured by a visual analog scale. Supplementary analgesia-Acetaminophen codein orally-was given at patient request. Statistical analysis was performed by the Mann-Whitnery U-test, Wilcoxon's test and the X[2] test as appropriate. All data are presented as mean +/- SD. With regard to demographic data, duration of anesthesia and tourniquet time, significant difference were not observed among groups A, B and C. Postoperatively, pain score during rest and movement were significantly higher in the I.V group than in the other groups [P< 0.05] and the difference between the B and C groups was also significant [P< 0.05]. Postoperatively, supplementary analgesic consumption was significantly decreased in the intraarticular Sufentanil and Sufentanil plus Methylprednisolone groups [P< 0.05], and the difference between the B and C groups was also significant [P< 0.05]. Intraarticular administration of Sufentanil alone and combination of Sufentanil and Methylprednisolone after knee meniscectomy are effective, reliable, and well-tolerated analgesic techniques. Sufentanil pluse Methyl-prednisolone reduced pain and use of supplementary analgesics effectively