Embryo production in buffaloes [Bubalus bubalis] with some supplementation in superovulatory regimens

The aim of this study is to evaluate the effect of different superovulatory regimens on embryo production of buffalo-cows in Egypt. Estrus synchronization applied on 16 multiparous Egyptian buffalo-cows divided randomize into three groups A [n=4], B [n=6] and C [n=6]. Only, thirteen buffalo cows responded in the three groups A [n=3]; B [n=4] and C [n=6]. The buffaloes showed estrus from the three groups were received a dose of 2500 IU of eCG on day 8 of the cycle. In group A [n=3] no, further superovulatory treatment was applied, whereas animals of group B [n=4] received a single dose of 2500 IU of hCG 30 h after AI. Buffaloes of group C [n=6] received the same regimen of group B in addition to i.m injection of 2.5 mg Estradiol benzoate [EB] and 50 mg progesterone [P4] 4 days before superovulatory treatments. Embryos were collected from all groups non-surgically during day 6 [around 140] h from estrus onset. The results reveals that there were a significance increase [P<0.05] for the number of corporalutea and collected embryos in group C than other treated groups. In conclusion, progesterone supplementation with estradiol benzoate 4 days before initiating the superovulation treatment seems to enhance the recovery rate in buffaloes. Further studies are needed in order to increase the number of embryos recovered per a buffalo female

Effect of helicobacter pylori infection on lipid profile in type II diabetic patients

The aim of this study is to investigate a possible relationship between H. pylori infection and dyslipidemia in diabetic patients. the study included twenty type 2 diabetic patients classified into two equal groups based on the presence of H. pylon infection [Gl] and its absence [G2]. Ten non-diabetic cases with H. pylori infection were also included [G3] and ten age matched nondiabetic and non H. pylori infected subjects were taken as controls [G4]. All patients and controls were subjected to history taking clinical examination and laboratory studies including fasting and post prandial blood glucose glycosylated hemoglubin, s. total cholesterol, s. triglyceride, HDL- cholesterol and LDL-cholesterol. H. pylori infection was diagnosed by the highely sensitive C13 urea breath test. Lipid profile is more atherogenic in H. pylori positive diabetic patients [G1] than H. pylori negative diabetic [G2].-The results revealed a statistically significant increase in trigleceride cholesterol LDL-cholesterol [G1>G2>G3>G4] versus a statistically significant decreas in HDL- cholesterol [GKG2 < G3 < G4. we concluded that there is a possible assoication between chronic H. pylori infection and atherogenic lipid profile and this assoication is higher among diabetic patients. The importance of this link is highlighted by the possibility of an effective intervention against H. pylori infection in type 2 diabetic patients as a preventable risk factor

Value of routine upper endoscopy before elective cholecystectomy

In a trial to detect the value of routine upper gatrointestinal endoscopy [UGE] before elective Cholecystectomy for treatment of proposed biliary dyspepsia, 110 patients who were preparing for Cholecystectomy operation, were examined one day before the operation by UGE. From these patients 34 [30.9%] were found to have clear nonbiliary causes for their dyspepsia and saved invasive surgical maneuver [peptic ulcers in 15 patients [13.6%], gastroesophygeal reflux disease [GERD] in 10 patients [9%] and H pylori in 9 patients [8.1%]]. In the remaining patients, 57 [51.8%] had duodeno-gastric reflux gastritis which may be a possible cause for their dyspepsia and 19 [17.2%] had normal UGE findings. Appropriate medical treatment of these endoscopic lesions in patients with clear cause of dyspepsia, led to absence of dyspeptic symptoms in 79.4%, and partial improvement in 20.6% while 36.8% of patients with possible causes of dyspepsia got marked improvement and 10.5% of them got partial improvement of symptoms after treatment. We concluded that routine UGE is mandatory before elective Cholecystectomy to exclude other medically treatable causes for dyspepsia. The procedure is safe, cost effective, yields definite diagnosis and diminishes pressure on gastroenterologists with reduction of outpatients consultations and inpatients unnecessary surgeries

Role of percutaneous transhepatic cholangiography and drainage [PTC and D] in cases of inaccessible endoscopic retrograde cholangiopancreatography [ERCP]

Endoscopic retrograde Cholangiopancreatography [ERCP] represents an important diagnostic and therapeutic tool in management of obstructive biliary lesions. Yet, the level of obstruction contributes to failure of this technique and represents hindering limitations. The purpose of this study was to evaluate the feasibility and role of percutaneous transhepatic Cholangiography and drainage [PTC and D] in management of inaccessible ERCP. Out of 318 obstructive jaundice patients scheduled for ERCP, 22 [6.9%] failed cases formed the subject of this study. ERCP trial failed due to advanced tumor infiltrating the papilla or the lower end of the common bile duct in 14/22 [63.6%] cases whereas in the remaining 8 cases, the distal end of CBD showed filling with non visualization of the rest of biliary tree. These cases were subjected to PTC and D using ultrasonography guided technique in16/22 [72,7%] cases and the blind technique in 6/22 [27.3%] patients. The obstructive jaundice proved to be due to advanced cancer head of pancreas in 8/22 cases, peri-ampullary carcinoma in 6/22 cases, advanced cholangiocarcinoma in 2/22 patients, hilar stricture in 2/22 cases, iatrogenic ligation of the CBD in 2/22cases and extra-hepatic sclerosing cholangitis in 2/22 cases. Further operative biliary reconstruction or palliative bypass were done in 10/22 cases. Two patients [0.9%] had complications in form of leak around the tube with subcutaneous collection in one case and slipped tube in the other. Two unrelated hospital deaths were reported. There was no biliary peritonitis, peritoneal hemorrhage, subdiaghragmatic collection nor failed case. This study highlights PTC and D as safe and applicable procedure resort to visualize and decompress the biliary tree in inaccessible ERCP cases

Age of onset of breast cancer among Iranian women

The age of onset of breast cancer in 1888 women in Iran for the years 1989 to 1994 was compared to that of 6000 cases reported from the U.S. for the years 1916 to 1966 .Despite inherent analytical limitations, it seems that cancer of the breast does occur at a younger age among Iranian woman