Frontal recess polyp in a 14-year-old child resembling an antro-choanal polyp

A rare case of a unilateral single nasal polyp arising from a left frontal recess resembling an antro-choanal polyp in a 14-year-old girl is presented. A polypoidal mass completely occupying the left nasal cavity extending to the anterior nares was evident by anterior rhinoscopy. The mass was excised endoscopically, and its origin was found to be the frontal recess of the left nasal cavity, a rare occurrence in the paediatric age group

Subclinical hypothyroidism in patients attending GMC hospital and its association with lipid disorders - a preliminary study

Subclinical hypothyroidism is a state characterized by mild elevations in Thyroid Stimulating Hormone [TSH] in patients without known thyroid disease. Clinical importance and therapy for subclinical hypothyroidism are subjects of both debate and research. To study the lipid disorders in patients with subclinical hypothyroidism referred from the Department of Internal Medicine, GMC Hospital and Research Centre, Ajman, UAE. Subjects referred to the laboratory for thyroid profiles between January and December 2009 were divided into three groups; Euthyroid [EUT], Subclinical Hypothyroid [SCH] and Overt Hypothyroid [OVH] based on TSH values 4 /= 10 mIU/ mL respectively. patients with diabetes, cardiovascular disease, dyslipidemia or on treatment for thyroid disorders were excluded. Serum lipid profiles of the subjects were investigated. PASW 18 software was used for analysis. One way ANOVA and Duncan multiple comparison tests were used to find the significance. of the 1234 subjects studied, 953 were females [77%] and 281 males [23%]. Mean age for the female subjects was 33+/- 10 years and for the male subjects 38 +/- 11 years. 95.5% were in the 19-59 year age group. 77 subjects [6.2%] were found to be SCH. Mean +/- SD total Cholesterol values were 223 +/- 33, 225 +/- 28, 253 +/- 35, LDL cholesterol values were 120 +/- 22, 130 +/- 21, 123 +/- 17 and Triglyceride levels were 99 +/- 21, 90 +/- 14, 130 +/- 45 mg/dl in the EUT, SCH and the OVH groups respectively. While there was no significant difference between the EUT and SCH group in the total Cholesterol and Triglyceride values, they were significantly different from the OVH group [p<0.05]. There were no differences in LDL cholesterol between the groups or lipid parameters between the genders. 6.2% of the patients referred were found to be SCH. There were no significant differences between the lipid parameters of EUT and SCH patients. OVH patients showed significantly higher total cholesterol and triglyceride levels in blood

Male infertility and its association with metabolic syndrome and hypogonadism

Hormonal profile alteration is seen in men with metabolic syndrome. Obese men have elevated levels of estrone and estradiol and there is also an attenuation of the pulse amplitude of luteinizing hormone [LH] which leads to a reduction of testicular production of testosterone. This study was conducted to assess the sperm morphology, prevalence of metabolic syndrome and association between gonadal hormones and parameters of metabolic syndrome among men diagnosed with infertility. Out of 434 men referred to the laboratory of Gulf Medical College Hospital and Research Centre, Ajman, UAE, 184 were diagnosed as infertile based on seminal parameters. Prevalence of metabolic syndrome and gonadal hormonal level among these infertile men were also studied. Data were analyzed with PASW 18 software and student t-test used for the significance. Mean age of the men referred for seminal analysis was 33 +/- 7.2 years. Forty two percent of the men were found to be infertile based on seminal parameters. Majority had total forward progression abnormality followed by abnormalities of head, tail and neck. Prevalence of metabolic syndrome among these men was found to be 19%. FSH and LH levels were significantly lower and prolactin levels were significantly higher [p<0.01] in men with metabolic syndrome. Estradiol and total testosterone levels showed no difference. High prevalence of metabolic syndrome was found among men diagnosed with infertility. Significant hypogonadism was found associated with metabolic syndrome among these men

Van der Knaap syndrome, a case from West Bengal, India

Leucodystrophies are a group of white matter diseases caused by an abnormality in the formation or maintenance of one or more components of the myelin sheath. The devastating course of the disease coupled with the lack of any defi nitive treatment render them potentially fatal and incurable. Van der Knaap Syndrome, also known as megaloencephalic leucoencephalopathy with subcortical cyst, is a relatively new and rare entity. Although reported sporadically from Europe, Asia and the Agarwal community in India, there is practically no case report from the eastern part of India. We present a case of van der Knaap syndrome in an adult female with some atypical features.

Effect of growth regulators on steroidal sapogenin and glycoalkaloid in tissue culture of solanum jasminoides

Callus tissues of Solanum jasminoides grown in RT medium were treated with 1, 3 and 5 ppm of aqueous IAA, NAA, 2, 4-D and Kinetin. The cultures were harvested at the end of 2nd, 4th, 6th and 8th week of the growth period, dried, weighed and their growth indices calculated. Tissues were also analyzed for their diosgenin, beta-sitosterol and solasodine contents. A linear increase in the growth index was recorded up to 3 ppm of all the growth regulators except NAA. Enhancement in diosgenin, beta-sitosterol and solasodine levels was found in tissues grown in different growth regulators, however, beta-sitosterol content was significantly higher in Kn supplementation