clinical study on the effect of shirodhara and jatamansayadi powder in the management of hypertension w.s.r. to [uccharaktachapa]

As man entered the 21[st] century with modernization in almost each and every walk of life, he has also paid for it by living in several stressful psychological conditions. The response to the psychological conditions varies from person to person because each has different psychic and bodily constitution. However, these stressors play certain roles in the development progression, prognosis as well as management of the disease. This stressful life-style affects one's mind and homeostasis of body by several psychosomatic mechanisms and causes many psychosomatic disorders. The 'Uccharaktachapa' [Essential Hypertension] is one of such diseases. Hypertension is the most prevalent cause for cerebrovascular and cardiovascular disorders, causing high rate of mortality and morbidity. So, hypertension is gaining more and more attention globally. Due to its high prevalence in our country, India is known as the Nation of Hypertension. Hypertension is also known as silent killer of mankind because most sufferers [85%] are asymptomatic and as per available reports, in more than 95% cases of hypertension the under lying cause is not found. Such patients are said to have Essential-Hypertension [EHT]

Impact of high plasma concentrations of dioxin and polychlorinated biphenyls [PCBS] in south Indian women with endometriosis

To estimate the levels of Dioxin and PCBs present in the plasma of women with different stages of endometriosis and relation between Dioxin, PCBs and their possible impact on the pathogenesis of endometriosis. A prospective case control study. Department of Reproductive Medicine, Bhagawan Mahavir Medical Research centre, Maternal Health and Research Trust, and Owaisi Hospital AND Research Center Hyderabad, Andhra Pradesh, India. 97 women with endometriosis undergoing laparoscopy and 102 controls. Heparinised blood samples were collected for dioxins, PCBs estimation. The levels of dioxins and PCBs were measured via gas chromatography. Women with endometriosis showed significantly higher concentrations of dioxin and PCBs when compared with the control group. The correlation between the concentrations of dioxin -TCDD, PCBs, and difference in the severity of endometriosis was strong and statistically significant at p<0.05 for all the four compounds PCB-1: r=+0.53; P<0.0001, PCB-5: r=+0.67; P<0.0001, PCB-29: r=+0.64; p<0.0001, PCB-98: r=+0.43; p<0.0014 and concentration of dioxin-TCDD: r=+0.36, p<0.0001. These results suggest that women having higher concentration of Dioxin and PCBs might have an increased susceptibility to endometriosis