Extramedullary plasmacytoma of base of tongue and soft palate

Extramedullary plasmacytoma of head and neck region is an uncommon malignant lesion with a propensity to involve upper respiratory tract. By its biological nature, it differs from solitary plasmacytoma of bone and myelomatosis. It is a distinctly separate clinical and pathological entity. local megavoltage radiation therapy is the treatment of choice, with salvage surgery for the persistent lesion. A report of two cases involving base of tongue, and soft palate with a brief review of the literature is presented

Limited wegener's granulomatosis

Wegener's granulomatosis is now recognized as a distinct and clinicopathological entity than any other vasculitides. The initial clinical features frequently include granulomatous vasculitis of the upper and lower respiratory tract and glomerulitis. Although the disease has been described as lethal in the past, prolonged survival and avoidance of end stage renal disease can now be expected when cyclophosphamide therapy is introduced early in the course