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Introduction: Nosocomial infection is a major problem globally. Methicillin-resistant Staphylococcus aureus (MRSA) remains one of the most important causes of nosocomial infections worldwide. MRSA are the important agents causing nosocomial infections. The study was conducted in the Department of Microbiology to determine the prevalence of MRSA and antibiotic susceptibility pattern. Material and Methods: This was a retrospective study conducted from July 2016 to August 2017 in a tertiary care hospital in Northern Bihar India. All isolates were identified in patients and data provided by the Clinical and Laboratory Standards Institute (CLSI) guidelines and antibiotic susceptibility pattern considered by Kirby Bauer disc diffusion method. The information was definitely recorded and analyzed using Microsoft Excel 2007 edition. Results: 200 Staphylococcus strains isolate of were isolated from various clinical samples, Out of 200 S. aureus isolates, 73 (36.5%) were methicillin resistant S. aureus (MRSA) and 127 (63.5%) were methicillin-sensitive S. aureus (MSSA) in our labs. Although, the majority of the MRSA isolates were resulted from pus samples 30, however, the S. aureus isolates resulted from post-operative wound infection was mostly MRSA. Conclusion: In conclusion, the importance of Isolation of MRSA patients and carriers in the hospitals, regular surveillance of hospital associated infections including monitoring antibiotic sensitivity pattern and strict drug policy for antibiotics may be helpful for reducing the incidence of these infections
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Perforation peritonitis is common cause of abdominal emergency. The morbidity and mortality associated with this condition is very high. Methods: The present hospital based study included 55 patients with perforation peritonitis admitted at the department of surgery. Data regarding clinical features, management and complications was noted. Results: Most of the patients had perforation in duodenum (58.2%). Pain abdomen was the most common complain (96.4%). Wound infection was seen in 23.6%, pneumonia in 27.3% and abdominal collection in18.2%. Conclusion: Timely diagnosis of perforation peritonitis is essential.
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The presence of derivative chromosome in a child with phenotypic features necessitates the need of parental karyotyping to ascertain the exact amount of loss or gain of the genetic material. The aim of this study was to emphasize the importance of parental karyotyping. Cytogenetic evaluation of the proband and his father were carried out at Laboratory. Cytogenetic analysis was performed on phytohemagglutinin stimulated cultures. The derivative chromosome 11 in proband was ascertained to have additional material from chromosome 6p arising from complex chromosomal rearrangement in the father. Karyotyping is the basic, cost-effective preliminary investigation in a child with mental subnormality or congenital anomalies.
Asunto(s)
Adulto , Preescolar , Cromosomas Humanos Par 3/genética , Cromosomas Humanos Par 6/genética , Cromosomas Humanos Par 11/genética , Asesoramiento Genético , Humanos , Discapacidad Intelectual/diagnóstico , Discapacidad Intelectual/epidemiología , Discapacidad Intelectual/genética , /métodos , Masculino , Translocación GenéticaRESUMEN
Acute macular neuroretinopathy (AMN) is a rare, macular disorder which typically affects young women who present with paracentral scotoma in one or both eyes corresponding to red, wedge-shaped parafoveal lesions. A young female presented with the complaints of few black spots (scotomas) in her visual field, which she noticed 1 month after a full-term normal delivery. Fundus examination showed flat, well-demarcated, reddish parafoveal lesions in both eyes, corresponding to the scotoma. Optical coherence tomography (OCT) at the site of lesion showed a well-delineated defect in the reflectivity of outer retinal layer. After 6 months of follow-up, fundus lesions were noted to be fading and repeat OCT revealed the realignment of the defect in the outer retinal reflectivity.