RESUMEN
Background: The present clinical trial was designed to evaluate the effects of bioactive glass in treatment of periodontal intra-bony defects. Methods: 25 patients 23-55 years of age with intra-bony defects completed 1 year study. After completion of initial therapy, defects were randomly assigned to either a test or control procedure. Following flap reflection root planning and removal of chronic inflammatory tissue in both groups test defects were restored with bioactive glass, while open flap debridement was done in control sites. Muco-periosteal flaps were replaced sutured and periodontal dressing was used. Follow up was carried out weekly, 3 months 9 months and 1 year post surgery. Plaque score, sulcus bleeding score probing pocket depth were recorded at baseline, 3 months and 1 year. Standardized radiographs using RVG was taken at baseline, immediately post operatively and at 1 year. Results: Radiographs showed a significant increase in radiographic density and volume between defects treated with bioglass when compared with open flap debridement alone. Probing pocket depth, probing attachment level showed improvement in test and control site with greater trend to improvement in test site. Conclusion: It was concluded that bioglass is effective as an adjunct to conventional surgery in treatment of intra-bony defects.