RESUMEN
The world faces a global crisis that encompasses health, financial, and psychological aspects as a result of the coronavirus disease. While the health crisis is significant, it is important to recognize that the human and social crises that have emerged are equally impactful. These crises have resulted in various negative outcomes, such as social rejection, economic disparity, unemployment, and mental distress. Fear is a significant psychological barrier that can impede recovery from any disease process, and thus, it plays a critical role in determining the mortality and morbidity of any given disease. The COVID-19 pandemic has generated a pervasive fear of infection that has further exacerbated the situation. This study explored the mechanisms by which humans may have elicited conditional fear, using the COVID-19 pandemic as a specific case study. Our goal was to examine the process of fear in humans by exploring our knowledge of neuroanatomy and the systemic response regulated by the autonomic nervous system.
RESUMEN
Background: Currently, there is no specific antiviral treatment and preventive vaccine against COVID-19. Stringent practice of preventive measures is recommended as the only way out for protecting oneself. However, uncertainties galore and the prevention cannot be guaranteed due to paucity of knowledge about the epidemiology of COVID-19. Nurses are in an ideal position to participate or play a key role in taking initiatives to enhance patient safety during COVID-19 pandemic. Their knowledge will help to break the transmission chain. Methods: In the present cross-sectional study an online questionnaire was used for data collection from nursing staff employed in a tertiary care centre/dedicated COVID hospital in central India. Universal sampling was done and the final sample size attained was 932. Data was cleaned, coded and analysis was done with statistical package for the social sciences (SPSS) version 20.0. Percentages, means and standard deviations (SD) were calculated and statistical tests in the form of t test and Wilcoxon rank-sum (Mann-Whitney) test were applied. Results: Social-media and television (TV) were the main sources of knowledge about COVID-19 for the study participants as reported by 76.82% and 74.25% respectively. Study participants were aware about the common symptom of COVID-19 like cough, 127 (13.63%), fever 30 (3.22%), and diarrhoea 80 (8.58%). Conclusions: Irrespective of their age and gender study participants had a fairly good knowledge about symptoms and prevention of COVID-19. Most of them were optimistic and had a positive attitude towards COVID-19 pandemic and resultant situation.
RESUMEN
AIM: The study objectives were evaluation of clinicopathological characteristics, correlations between the preoperative and postoperative tumor grades, and their implications on lymph node metastasis. MATERIALS AND METHODS: We conducted a retrospective descriptive study of 131 cases of endometrial cancer examined and treated at a tertiary regional cancer institute between the years 2003 and 2009. We reviewed the oncology database as well as the clinical records and surgico‑pathological registry of all these patients. STATISTICAL METHODS USED: All the summary measure computation and Chi‑square test for comparing more than one proportion was done in spreadsheet (Excel). RESULTS: The multiparity association with endometrial cancer was commonly seen 113/131 (86.2%). Twelve (9.7%) patients preoperatively diagnosed as Grade 1 tumors upgraded to Grade 3 changes in postoperative specimens and six of these 12 patients (50%) had lymph node metastasis. A total of 14/131 (10.6%) cases had lymph nodes metastasis. CONCLUSIONS: There is a poor correlation between the preoperative and the postoperative tumor grades. Routine pelvic lymphadenectomy may be a valuable method in low‑risk cases and para‑aortic lymphadenectomy may be limited to high‑risk endometrial cancers.