RESUMEN
Polyglandular autoimmunity (PGA) type 2 presenting in childhood is extremely rare. We report a case of type 2 PGA who had hypothyroidism, followed by diabetic ketoacidosis and was later diagnosed to have adrenal insufficiency also.
Asunto(s)
Adolescente , Diabetes Mellitus Tipo 2/complicaciones , Humanos , Poliendocrinopatías Autoinmunes/complicacionesRESUMEN
The etiology of slipped capital femoral epiphysis (SCFE) is unknown, though hormonal as well as mechanical factors have been implicated. We report a case of gigantism who presented with SCFE. This case provides an insight into the genesis of SCFE, which in this case was related to growth hormone excess and sex-hormone deficiency.
Asunto(s)
Adulto , Constitución Corporal , Epífisis Desprendida/etiología , Cabeza Femoral/diagnóstico por imagen , Gigantismo/complicaciones , Hormonas Esteroides Gonadales/deficiencia , Trastornos del Crecimiento/complicaciones , Hormona del Crecimiento/efectos adversos , Humanos , Fijadores Internos , MasculinoRESUMEN
Hyperthyroidism is seen in 3.5-26% of acromegalic subjects, and can occur through TSH-dependent or independent mechanisms. Thyrotoxicosis as the first presenting illness in acromegaly is particularly uncommon, as described in this patient who had both acromegaly and a toxic thyroid adenoma.