Microbiological study of vaginal discharge associated with the use of CuT 200.

A microbiological study of the vaginal discharge was conducted on 75 women attending family planning outdoors. In 24 out of 25 symptomatic CuT 200 users suffering from non-specific vaginitis, Gardnerella vaginalis was isolated from 19 cases (79%). The difference in the recovery rate of Gardnerella vaginalis was highly significant between symptomatic CuT 200 users and non-users (p less than 0.001) and that between symptomatic and asymptomatic CuT 200 users (p less than 0.05). But the difference between asymptomatic CuT 200 users and non-users was not statistically significant. The presence of clue cells on direct Gram's staining of vaginal discharge is significantly (p less than 0.05) related to the recovery of Gardnerella vaginalis on culture.

Gardnerella vaginalis vaginitis in Cu T 200 users.

Vaginal samples obtained from intrauterine contraceptive device (IUD) users with and without vaginitis and from healthy non-users were studied for presence of G. vaginalis and cytological changes. Vaginitis was present in 29.5 per cent IUD users and most of them (76%) yielded G. vaginalis. G. vaginalis was also recovered from asymptomatic IUD users and from non-users, but heavy colonisation was infrequent. The presence of clue cells and many small Gram negative bacilli and scanty lactobacilli were associated with G. vaginalis recovery. Inflammation was more frequent in IUD users than in non-users (P less than 0.001). A significant correlation was also found between inflammatory changes and G. vaginalis colonisation among all groups of patients.