Ultrastructural study of skeletal muscle development

Myogenesis of skeletal muscles were viewed by Electron microscope. They were taken from the abdominal wall of fetal [both sexes] and neonatal male rabbits. revealed that myoblasts and young myotubes appeared at day 15 of gestation. By day 19 the myofibrils of maturing myotube have clear Z - lines, while at day 24 of gestation the myofibrils develop a full banding pattern with very clear Z-lines. Newborn rabbit muscles display very well developed and uniform banding pattern. The observations showed that male muscle development preceed that of the female at the same age. The distinctive results of this work is the proliferation of maturing muscle nucleus, which are so far not documented by any other researcher