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1.
Int. braz. j. urol ; 30(6): 479-486, Nov.-Dec. 2004. tab
Artículo en Inglés | LILACS | ID: lil-397809

RESUMEN

OBJECTIVE: To evaluate the concurrent validity, internal consistency and responsiveness of King's Health Questionnaire (KHQ) in patients who underwent sling procedures for the treatment of stress urinary incontinence. MATERIALS AND METHODS: We performed a prospective open label multicenter study in 4 tertiary referral centers. Sixty-eight female patients were enrolled with urodynamically diagnosed urinary stress incontinence. Patients were treated using surgical procedures, mostly (73 percent) with the synthetic sling procedure, which has been considered one of the gold standard methods for the treatment of urinary incontinence. The patients were assessed before and after one month of postoperative follow up, using the KHQ in its validated Portuguese version. Patients also underwent preoperative urodynamic test, Stamey incontinence grading, pad usage and the assessment of number of pads used per day. After surgery, patients underwent stress test, Stamey incontinence grading pad usage and the assessment of number of pads used per day. RESULTS: The concurrent validity showed good correlations in some domains of KHQ to clinical parameters. The internal consistency was higher after treatment compared to preoperative values. Objective parameters, such as pad usage and the assessment of number of pads used per day, had significant correlation with changes in post-treatment scores on KHQ. The responsiveness expressed in terms of standardized effect size (SES) and standardized response mean (SRM) was large. CONCLUSION: The results showed moderate concurrent validity, strong internal consistency and high responsiveness for KHQ, indicating that it is suitable for measuring outcomes in clinical trials among female patients with stress urinary incontinence.


Asunto(s)
Femenino , Humanos , Indicadores de Salud , Encuestas y Cuestionarios , Incontinencia Urinaria de Esfuerzo/cirugía , Periodo Posoperatorio , Estudios Prospectivos , Prótesis e Implantes , Calidad de Vida , Reproducibilidad de los Resultados
2.
Int. braz. j. urol ; 29(6): 524-527, Nov.-Dec. 2003. ilus
Artículo en Inglés | LILACS | ID: lil-364409

RESUMEN

Post-prostatectomy urinary incontinence is an uncommon complication of adenomectomies, occurring in approximately 1 percent of cases and being more frequent following radical prostatectomies. There is a significant implication in the quality of life for these patients. The surgical techniques employed for its treatment are the implantation of an artificial sphincter, peri-urethral injections and suburethral slings. Considering the low efficacy of peri-urethral injections and the high cost of artificial sphincters, we present in this work a technical modification of the suburethral sling, whose preliminary results are satisfactory. The fundamental modification in this technique is due to the replacement of the synthetic material usually employed for making the sling for autologous tissue, constituted by an aponeurotic strip taken from the rectus muscle of abdomen. This modification aims to minimize risks of urethral erosion that, despite it was not described in this population due to the use of synthetic materials, is a possibility when facing the tension that is used over the bulbar urethra. In addition to such aspects the autologous aponeurosis does not have a cost except for a short prolongation of the surgical act.

3.
Braz. j. urol ; 28(1): 25-32, jan.-fev. 2002. tab
Artículo en Inglés, Portugués | LILACS | ID: lil-324209

RESUMEN

Introduçäo: Os alfa-bloqueadores säo hoje as drogas de escolha no tratamento clínico de pacientes com hiperplasia prostática benigna (HPB). Os autores apresentam os resultados de um estudo prospectivo, randomizado, duplo-cego, e controlado por placebo da alfuzosina no tratamento de pacientes com HPB. Material e métodos: 31 pacientes foram randomizados em dois grupos: alfa-bloqueador seletivo alfuzosina na dose de 5 mg duas vezes ao dia (n=16) ou placebo (n=15) por 12 semanas. Os pacientes foram selecionados de acordo com critérios de inclusäo e exclusäo que, de forma geral, incluiram pacientes com 50 anos de idade ou mais, escore internacional de sintomas prostáticos (EISP) de 12 pontos, índice de qualidade de vida (IQV) de 3 pontos ou mais, e fluxo urinário máximo (Fmáx) entre 5 e 15 ml/s. Resultados: Näo houve diferença na taxa de melhora do EISP (37 por cento versus 29 por cento, p=0,446) e IQV (15 por cento versus 21 por cento, p=0,446) entre o grupo alfuzosina e o grupo placebo. No entanto, embora marginalmente significante, o Fmáx mostrou uma melhora marcante após a alfuzosina quando comparado ao placebo (50 por cento versus 5,5 por cento, p=0,06). A incidência de efeitos colaterais foi similar em ambos os grupos, alfuzosina e placebo (43,8 por cento versus 40 por cento, respectivamente). Conclusöes: O alfa-bloqueador alfuzosina näo é uma panacéia e, em alguns pacientes, a melhora clínica ocorre principalmente devido ao efeito placebo, que neste estudo resultou em aproximadamente 30 por cento de melhora do EISP (p=0,001), 21 por cento de melhora do IQV (p=0,017) e um aumento do Fmáx ò50 por cento em 26,5 por cento dos pacientes. Entretanto, o alfa-bloqueador alfuzosina tem um papel importante na abordagem clínica da HPB, já que seu mecanismo de açäo alivia o componente dinâmico da obstruçäo prostática, como demonstrado pela melhora do Fmáx.


Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Antagonistas Adrenérgicos alfa/uso terapéutico , Hiperplasia Prostática/tratamiento farmacológico , Quinazolinas , Antagonistas Adrenérgicos alfa/administración & dosificación , Antagonistas Adrenérgicos alfa/efectos adversos , Método Doble Ciego , Quinazolinas
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